Table 2 Change in echocardiographic measurements at 48 weeks stratified by treatment and genotype
From: Adipocyte-derived leucine aminopeptidase genotype and response to antihypertensive therapy
Irbesartan | Atenolol | |||||
|---|---|---|---|---|---|---|
Lys/Lys (n = 3) | Lys/Arg (n = 16) | Arg/Arg (n = 24) | Lys/Lys (n = 6) | Lys/Arg (n = 19) | Arg/Arg (n = 22) | |
IVS (mm) | -0.12 [0.1] | -0.21 [0.04] | -0.19 [0.04] | -0.15 [0.06] | -0.11 [0.04] | -0.14 [0.03] |
IVS (mm) – multivariate | -0.11 [0.1] | -0.22 [0.04] | -0.18 [0.03] | -0.20 [0.07] | -0.14 [0.04] | -0.099 [0.04] |
PWT (mm) | -0.043 [0.07] | -0.055 [0.03] | -0.13 [0.03] | -0.11 [0.05] | -0.041 [0.03] | -0.13 [0.03] |
PWT (mm) – multivariate | -0.032 [0.07] | -0.073 [0.03] | -0.12 [0.02] | -0.070 [0.06] | -0.051 [0.03] | -0.13 [0.03] |
LVEDD (mm) | 0.077 [0.2] | 0.17 [0.09] | -0.063 [0.07] | -0.037 [0.1] | 0.11 [0.07] | 0.17 [0.07] |
LVEDD (mm) – multivariate | -0.13 [0.2] | 0.15 [0.07] | -0.029 [0.06] | 0.016 [0.2] | 0.11 [0.08] | 0.17 [0.07] |