Endpoint | Difference | Assumptions | Precision of estimate | |
---|---|---|---|---|
 |  |  | 95% | 99% |
Mean serum cholesterol/ mMol/L | 0.4 | Sda = 1.3 | ± 0.24 | ± 0.32 |
Systolic blood pressure/ mmHg | 6 | sd = 21 | ± 3.9 | ± 5.1 |
Shuttle-walk test/10 metre shuttles | 6 | sd=b20 or sd = * 40 | ± 3.7 ± 7.4 | ± 4.9 ± 9.7 |
HADSc anxiety | 1.5 | sd = 4.5 | ± 0.83 | ± 1.1 |
HADSc depression | 1.5 | sd = 4.0 | ± 0.74 | ± 0.97 |
Smoking cessation | 20% (Jolly [66]) | 45% smokers at baseline (effective sample size approx 200) 50% give up in hospital-based group | 9%, 33% | 5%, 37% |