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Table 1 Comparison of the patients with the 3243A> G mutation and the matched controls.

From: Cardiac abnormalities in patients with mitochondrial DNA mutation 3243A>G

  Patients with 3243A>G Controls p-value
Gender (% men) 38.5 38.5 1.00
Age (yrs) 46.7 ± 12.7 46.8 ± 11.5 0.63
Hypertension (n) 10 10 1.00
Diabetes mellitus (n) 20 7 0.001
Left ventricular dimensions    
ST(D) (mm) 12.2 ± 3.2 10.0 ± 1.7 0.003
PWT(D) (mm) 12.1 ± 3.7 10.0 ± 1.8 0.02
LVD(D) (mm) 43.4 ± 5.8 49.6 ± 5.4 <0.001
LVH* (n) 19 6 0.002
Left ventricular mass    
LVMI (g/m2) 127 ± 54 102 ± 24 0.06
LVH (n) 12 3 0.02
  1. ST(D), thickness of interventricular septum in diastole; PWT(D), thickness of posterior ventricular wall in diastole; LVD(D), left ventricular end-diastolic diameter; LVH*, left ventricular hypertrophy = septal or posterior wall end-diastolic thickness ≥ 12 mm in non-hypertensives and ≥ 14 mm in medically treated hypertensives [23]; LVMI, left ventricular mass/body surface area, where LVM is left ventricular mass calculated by the method of American Society of Echocardiography: 0.8 × (1.04 × ((LVID/10 + IVS/10 + PVW/10)3 – (LVID/10)3) + 0.6 [24, 25]; LVH, left ventricular hypertrophy = LVMI over 134 g/m2 for men and 110 g/m2 for women [25]. Values are means ± standard deviations.