From: Expression of TGF-β1 and β3 but not apoptosis factors relates to flow-induced aortic enlargement
Time points | Blood flow (mL/min) | WSS (Pa) | Lumen diameter (mm) | Wall thickness (mm) | BrdU Rate (EC) (per section) | BrdU Rate (SMC) (per section) |
---|---|---|---|---|---|---|
Ctrl1 | 8.0 ± 1.0 | 5.2 ± 0.7 | 0.918 ± 0.104 | 0.075 ± 0.004 | 0.6 ± 0.8 | 0.2 ± 0.3 |
1D | 42.5 ± 5.3* | 36.5 ± 4.6* | 0.838 ± 0.088 | 0.068 ± 0.004 | 4.2 ± 4.3 | 2.8 ± 2.9 |
3D | 52.3 ± 28.6* | 41.9 ± 22.9* | 0.866 ± 0.041 | 0.063 ± 0.003 | 2.9 ± 2.2 | 1.5 ± 1.5 |
1W | 40.3 ± 17.7* | 23.2 ± 10.2* | 0.960 ± 0.030 | 0.057 ± 0.004 | 3.6 ± 1.6* | 1.4 ± 1.2 |
2W | 43.5 ± 13.0* | 13.5 ± 4.0* | 1.188 ± 0.078* | 0.044 ± 0.002* | 4.1 ± 3.2* | 1.4 ± 0.8 |
4W | 46.2 ± 6.8* | 10.2 ± 1.5* | 1.322 ± 0.0751* | 0.036 ± 0.003* | 4.0 ± 0.9* | 2.5 ± 2.3* |
8W | 46.3 ± 9.3* | 5.8 ± 1.2 | 1.604 ± 0.162* | 0.030 ± 0.003* | 7.5 ± 0.7* | 1.5 ± 0.7 |