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Table 1 Hemodynamic Parameters, Morphometry, BrdU Incorporation Rate, and Apoptosis Rate

From: Expression of TGF-β1 and β3 but not apoptosis factors relates to flow-induced aortic enlargement

Time

points

Blood flow

(mL/min)

WSS

(Pa)

Lumen diameter

(mm)

Wall thickness

(mm)

BrdU Rate

(EC)

(per section)

BrdU Rate

(SMC)

(per section)

Ctrl1

8.0 ± 1.0

5.2 ± 0.7

0.918 ± 0.104

0.075 ± 0.004

0.6 ± 0.8

0.2 ± 0.3

1D

42.5 ± 5.3*

36.5 ± 4.6*

0.838 ± 0.088

0.068 ± 0.004

4.2 ± 4.3

2.8 ± 2.9

3D

52.3 ± 28.6*

41.9 ± 22.9*

0.866 ± 0.041

0.063 ± 0.003

2.9 ± 2.2

1.5 ± 1.5

1W

40.3 ± 17.7*

23.2 ± 10.2*

0.960 ± 0.030

0.057 ± 0.004

3.6 ± 1.6*

1.4 ± 1.2

2W

43.5 ± 13.0*

13.5 ± 4.0*

1.188 ± 0.078*

0.044 ± 0.002*

4.1 ± 3.2*

1.4 ± 0.8

4W

46.2 ± 6.8*

10.2 ± 1.5*

1.322 ± 0.0751*

0.036 ± 0.003*

4.0 ± 0.9*

2.5 ± 2.3*

8W

46.3 ± 9.3*

5.8 ± 1.2

1.604 ± 0.162*

0.030 ± 0.003*

7.5 ± 0.7*

1.5 ± 0.7

  1. 1 Values of all controls were pooled. * P < 0.05 as compared to controls