From: ACTN3R577X polymorphism and long-term survival in patients with chronic heart failure
Variables | HR | 95% CI | p value |
---|---|---|---|
RX or XX genotypes for the ACTN3 R577X | 1.72 | 1.14-2.62 | 0.01 |
Gender (male) | 1.19 | 0.78-1.81 | 0.42 |
Age (years) | 1.00 | 0.98-1.02 | 0.70 |
Body mass index (kg/m2) | 0.99 | 0.95-1.04 | 0.93 |
Ethnicity (White vs Non-White) | 1.24 | 0.78-1.94 | 0.36 |
Hemoglobin (g/dL) | 0.87 | 0.79-0.94 | 0.002 |
Creatinine (mg/dL) | 2.16 | 1.69-2.76 | 0.001 |
LVEF (%) | 0.98 | 0.97-0.99 | 0.02 |
Etiology | |||
Chagasic (reference) | 1.00 | ||
Idiopathic | 0.58 | 0.28-1.21 | 0.15 |
Hypertensive | 0.50 | 0.26-0.97 | 0.04 |
Ischemic | 0.74 | 0.42-1.32 | 0.31 |
Valve disease | 0.70 | 0.35-1.40 | 0.32 |