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Table 2 Cox proportional-hazards model for mortality in patients with heart failure

From: ACTN3R577X polymorphism and long-term survival in patients with chronic heart failure

Variables

HR

95% CI

p value

RX or XX genotypes for the ACTN3 R577X

1.72

1.14-2.62

0.01

Gender (male)

1.19

0.78-1.81

0.42

Age (years)

1.00

0.98-1.02

0.70

Body mass index (kg/m2)

0.99

0.95-1.04

0.93

Ethnicity (White vs Non-White)

1.24

0.78-1.94

0.36

Hemoglobin (g/dL)

0.87

0.79-0.94

0.002

Creatinine (mg/dL)

2.16

1.69-2.76

0.001

LVEF (%)

0.98

0.97-0.99

0.02

Etiology

   

Chagasic (reference)

1.00

  

Idiopathic

0.58

0.28-1.21

0.15

Hypertensive

0.50

0.26-0.97

0.04

Ischemic

0.74

0.42-1.32

0.31

Valve disease

0.70

0.35-1.40

0.32

  1. HR: Hazard ratio; LVEF: Left ventricular ejection fraction.