Table 4 Risk of T2DM by statin use, stratified by age groups, BMI categories, hypertension, CVD and follow-up time
PS [5-95%] | Incident T2DM per 1000 person-years (95% CI) | Hazard ratio (95% CI) adjusted for age and propensity score | |
|---|---|---|---|
(N = 1,448,993) | Exposed | Unexposed | |
Age | Â | Â | Â |
30-39 | 23.16 (21.70-24.72) | 3.89 (3.59-4.21) | 4.68 (4.12-5.31) |
40-49 | 25.13 (24.43-25.84) | 6.70 (6.80-7.20) | 2.84 (2.70-2.99) |
50-59 | 25.22 (24.79-25.65) | 10.83 (10.65-11.00) | 1.87 (1.82-1.93) |
60-69 | 23.88 (23.52-24.23) | 14.53 (14.31-14.75) | 1.34 (1.30-1.37) |
70-79 | 22.94 (22.52-23.36) | 17.81 (17.49-18.14) | 1.15 (1.11-1.19) |
80-85 | 20.30 (19.48-21.15) | 13.83 (13.32-14.36) | 1.25 (1.17-1.34) |
BMI, kg/m 2 | Â | Â | Â |
<20 | 11.71 (10.79-12.70) | 6.76 (6.38-7.15) | 1.20 (1.06-1.36) |
20-25 | 13.22 (12.92-13.53) | 6.54 (6.41-6.67) | 1.51 (1.45-1.57) |
>25 | 28.99 (28.72-29.75) | 17.18 (17.01-17.35) | 1.40 (1.38-1.43) |
Hypertension | 26.41 (26.06-26.77) | 21.80 (21.49-22.12) | 1.04 (1.01-1.07) |
No hypertension | 22.32 (22.06-22.57) | 9.69 (9.58-9.80) | 1.92 (1.88-1.95) |
CVD | 23.42 (23.00-23.85) | 21.91 (21.32-22.53) | 0.86 (0.82-0.89) |
No CVD | 24.04 (23.80-24.28) | 11.63 (11.53-11.74) | 1.70 (1.67-1.72) |
Follow up time (years) | Â | Â | Â |
0-1Â yr | 19.97 (19.52-20.42) | 11.53 (11.33-11.74) | 1.52 (1.47-1.57) |
1-3Â yr | 20.11 (19.77-20.44) | 13.55 (13.37-13.74) | 1.22 (1.19-1.25) |
3-5Â yr | 24.56 (24.12-25.00) | 11.61 (11.38-11.84) | 1.73 (1.68-1.80) |
5-10Â yr | 30.04 (29.55-30.53) | 10.85 (10.59-11.12) | 2.25 (2.17-2.34) |
10-15Â yr | 34.93 (33.52-36.39) | 10.20 (9.38-11.10) | 3.05 (2.71-3.43) |
15-20Â yr | 42.24 (36.90-48.36) | 12.24 (9.08-16.51) | 3.63 (2.44-5.38) |
20-25Â yr | 13.10 (1.84-93.00) | n.e. | n.e. |