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Table 2 Baseline characteristics of patients who developed T2DM

From: Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink

Baseline characteristics Subjects with incident T2DM Subjects without incident T2DM
n (%) n (%)
All patients (n = 2,016,094) 130,395 (6.47) 1,885,699 (93.53)
Gender   
Male 70,972 (54.43) 995,813 (52.81)
Female 59,423 (45.57) 889,886 (47.19)
Age mean (sd), yrs 63.44 (10.54) 62.19 (11.24)
30-39 1,697 (1.30) 43,108 (2.29)
40-49 11,324 (8.68) 209,938 (11.13)
50-59 33,703 (25.85) 522,025 (27.68)
60-69 43,636 (33.46) 592,927 (31.44)
70-79 32,174 (24.67) 389,694 (20.67)
80-85 7,861 (6.03) 128,007 (6.79)
BMI, kg/m 2   
 <20 2,461 (1.89) 74,258 (3.94)
 20-25 20,947 (16.06) 544,004 (28.85)
 >25 102,001 (78.22) 1,020,270 (54.11)
 Unknown 4,986 (3.82) 247,167 (13.11)
Smoking status   
Current smokers 21,742 (16.67) 335,261 (17.78)
Former smoker 59,403 (45.56) 636,260 (33.74)
Non-smoker/never 48,775 (37.41) 833,493 (44.20)
Unknown status 475 (0.36) 80,685 (4.28)
Alcohol use   
Current (unknown amount) 5,044 (3.87) 59,727 (3.17)
Rare drinker (<2u/d) 21,939 (16.83) 271,032 (14.37)
Moderate drinker (3-6u/d) 64,639 (49.57) 916,543 (48.60)
Excessive drinker (>6u/d) 40,912 (9.49) 135,790 (8.57)
Past use 4,200 (3.22) 44,267 (2.35)
Non-drinker 17,844 (13.68) 197,361 (10.47)
Unknown status 5,809 (4.45) 230,987 (12.25)
Family history of:   
Diabetes 6,607 (5.07) 67,269 (3.57)
Cardiovascular disease 29,012 (22.25) 391,498 (20.76)
Diagnosis of:   
Hyperlipidaemia 6,372 (4.89) 53,045 (2.81)
Atherosclerosis 373 (0.29) 3.466 (0.18)
Hypertension 50,529 (38.75) 478,788 (25.39)
Heart failure 3,235 (2.48) 27,373 (1.45)
Cardiovascular disease 20,852 (15.99) 179,553 (9.52)
Atrial fibrillation 5,117 (3.92) 48,795 (2.59)
Hepatic disease (within 6 months) 787 (0.60) 6,757 (0.36)
Kidney disease (within 6 months) 2,671 (2.05) 38,494 (2.04)
Abnormal glucose level 3,780 (2.90) 14,053 (0.75)
Osteoporosis 3,099 (2.38) 55,210 (2.93)
Cancer 12,916 (9.91) 189,677 (10.06)
Thyroid disease 10,747 (8.24) 129,671 (6.88)
Prior use of:   
Antipsychotics (within 6 months) 114 ( 0.09) 1,455 (0.08)
Antidepressants (within 6 months) 1,503 (1.15) 19,868 (1.05)
Cardiovascular drugs 53,096 (40.72) 680,014 (36.06)
Nonstatin lipid lowerers (within 3 months) 189 (0.14) 1,041 (0.06)
Systemic glucocorticoids (within 6 months) 1,496 (1.15) 18,475 (0.98)
Oestrogens/HRT (within 1 year) 706 (0.54) 8,781 (0.47)
Bisphosphonates 699 (0.54) 11,765 (0.62)
CYP450 3A4 inhibitor 1,709 (1.31) 18,616 (0.99)
Annual consultation rate, mean (SD) 22.16 (19.33) 17.66 (18.04)
Annual prescription rate, mean (SD) 19.42 (30.12) 11.57 (24.27)
  1. All the differences between groups were significant at the 0.05 level (two-sided).