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Table 3 Time effects on markers of subclinical atherosclerosis and anthropometric and cardiometabolic profiles

From: Effects of weight management by exercise modes on markers of subclinical atherosclerosis and cardiometabolic profile among women with abdominal obesity: a randomized controlled trial

 

Modified intention-to-teat analysis (N = 92)

Per-protocol analysis (N = 49)

 

Mean (SD)

Pa

Mean (SD)

Pa

FMD (mm)

    

 3 M

10.93 (3.57)

.676

11.23 (3.67)

.628

 6 M

11.33 (3.84)

 

1171 (4.17)

 

 9 M

11.41 (4.20)

 

11.54 (4.57)

 

 12 M

11.11 (4.18)

 

10.93 (4.47)

 

PWV (m/sec)

    

 3 M

7.89 (1.14)

.048‡

7.60 (0.87)

.055

 6 M

7.72 (1.19)

 

7.36 (0.88)

 

 9 M

7.88 (1.19)

 

7.57 (1.00)

 

 12 M

7.87 (1.15)

 

7.56 (0.88)

 

IMT (mm)

    

 3 M

0.70 (0.16)

.018†‡

0.71 (0.19)

.042

 6 M

0.67 (0.14)

 

0.67 (0.16)

 

 9 M

0.68 (0.13)

 

0.70 (0.13)

 

 12 M

0.69 (0.13)

 

0.71 (0.13)

 

Body weight (kg)

    

 3 M

70.45 (10.86)

<.001*†‡

67.84 (9.46)

<.001*†‡

 6 M

68.95 (11.37)

 

65.81 (9.87)

 

 9 M

68.96 (11.41)

 

65.08 (7.84)

 

 12 M

69.04 (11.55)

 

66.03 (10.14)

 

Lean body mass (kg)

    

 3 M

45.29 (4.97)

.040*

44.65 (5.01)

.153

 6 M

45.14 (5.02)

 

44.40 (5.08)

 

 9 M

45.08 (4.96)

 

44.10 (4.29)

 

 12 M

44.99 (4.89)

 

44.28 (4.86)

 

WC (cm)

    

 3 M

92.80 ( 9.21)

<.001*†‡

89.88 (7.01)

<.001†

 6 M

90.82 (10.10)

 

87.09 (7.95)

 

 9 M

90.85 (10.08)

 

87.14 (7.26)

 

 12 M

91.39 ( 9.81)

 

88.42 (7.60)

 

Systolic BP(mmHg)

    

 3 M

114.30 (15.41)

.245

111.57 (12.21)

.253

 6 M

112.77 (14.80)

 

110.03 (13.00)

 

 9 M

113.59 (14.18)

 

110.43 (10.65)

 

 12 M

113.08 (14.69)

 

109.57 (11.51)

 

TC (mg/dL)

    

 3 M

196.93 (38.15)

.006‡

195.40 (42.20)

.013‡

 6 M

196.73 (36.47)

 

192.33 (37.43)

 

 9 M

203.46 (38.37)

 

201.86 (41.14)

 

 12 M

199.39 (41.15)

 

194.66 (45.70)

 

LDL-C (mg/dL)

    

 3 M

118.64 (35.38)

.020‡

118.13 (41.36)

.034‡

 6 M

118.52 (31.52)

 

115.88 (34.15)

 

 9 M

123.07 (36.68)

 

121.74 (41.40)

 

 12 M

118.76 (38.17)

 

115.65 (43.25)

 

HDL-C (mg/dL)

    

 3 M

52.07 (11.78)

<.001*

51.59 (12.63)

<.001*

 6 M

54.01 (12.54)

 

53.97 (14.28)

 

 9 M

55.34 (12.25)

 

56.92 (13.64)

 

 12 M

56.47 (13.26)

 

57.59 (14.06)

 

Triglycerides (mg/dL)

    

 3 M

131.12 (77.41)

.289

128.39 (90.15)

.197

 6 M

121.00 (62.72)

 

112.40 (60.51)

 

 9 M

125.25 (71.84)

 

115.99 (77.68)

 

 12 M

120.55 (68.62)

 

106.64 (68.35)

 

Fasting glucose (mg/dL)

    

 3 M

90.65 (13.13)

<.001†

89.09 (9.52)

.034*†

 6 M

87.42 (12.54)

 

85.13 (9.33)

 

 9 M

87.29 (14.41)

 

85.60 (13.13)

 

 12 M

89.62 (13.70)

 

88.23 (11.93)

 

VO2max (mL/kg/min)

    

 3 M

32.06 (5.27)

<.001*†‡

33.23 (4.34)

<.001*†

 6 M

35.24 (6.44)

 

37.04 (4.63)

 

 9 M

35.14 (6.26)

 

37.05 (4.97)

 

 12 M

34.48 (6.21)

 

36.02 (5.15)

 
  1. aP-values for an equality of mean values across periods; Significance of trend tests: *Linear trend, †Quadratic trend, ‡Cubic trend.
  2. FMD = flow mediated dilation; PWV = pulse wave velocity; IMT = intima media thickness; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; SD = standard deviation; TC = total cholesterol; VO2max = maximal oxygen consumption; WC = waist circumference.
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