Figure 3
From: Cholesterol efflux is LXRα isoform-dependent in human macrophages
The baseline protein expression levels of ABCA1, ABCG1 and SR-BI depend on LXRα, but not LXRβ in human macrophages. Human macrophages were transfected with non-targeting control, LXRα siRNA, or LXRβ siRNA, and then incubated for 96 h. ABCA1, ABCG1, SR-BI, LXRα and LXRβ protein expression levels were measured by immunoblotting (A, B and C). Similar results were obtained in three independent experiments. Data are presented as Mean ± SEM, *P < 0.05 (vs non-targeting control).