Figure 1
From: Cholesterol efflux is LXRα isoform-dependent in human macrophages
LXRs agonist T0901317 enhances cholesterol efflux from human macrophages. Following 24 h of labeling with [3H]-cholesterol, human macrophages were treated with T0901317 or the vehicle for 48 h. Cells were then washed with PBS, and assayed for apoA-I- (A) or HDL- (B) mediated cholesterol efflux as described under the Methods. Data in each group were obtained from triplicate flasks. Data are presented as Mean ± SEM, *P < 0.05 (vs control).