Skip to main content

Table 2 Patient characteristics categorized by plasma hs-CRP or big-ET levels 1

From: Plasma NT pro-BNP, hs-CRP and big-ET levels at admission as prognostic markers of survival in hospitalized patients with dilated cardiomyopathy: a single-center cohort study

 

All of the patients (n = 622)

hs-CRP < 3.91 mg/L (n = 375)

hs-CRP > 3.91 mg/L (n = 247)

P value

Big ET < 0.95 pmol/mL (n = 335)

Big ET > 0.95 pmol/mL (n = 287)

P value

Age (years)

50.1 ± 14.3

50.1 ± 14.1

52.5 ± 14.2

0.051

51.2 ± 14.1

51.0 ± 14.5

0.846

Female sex, n (%)

160 (25.7)

102 (27.2)

58 (23.5)

0.299

88 (26.3)

72 (25.1)

0.737

History

       

Course

3 (0.5-7)

2 (0.35-7)

3 (0.6-6)

0.170

3 (0.5-6)

2.5 (0.35-7)

0.628

Diabetes mellitus

92 (14.8)

57 (15.2)

35 (14.2)

0.723

45 (13.4)

47 (16.4)

0.303

Atrial fibrillation, n (%)

142 (22.8)

79 (21.1)

63 (25.5)

0.197

62 (18.5)

80 (27.9)

0.006

Smoker, n (%)2

294 (47.3)

172 (45.9)

122 (49.4)

0.396

159 (47.5)

135 (47.0)

0.953

Drinker, n (%)2

190 (30.5)

119 (31.7)

71 (28.7)

0.422

103 (30.7)

87 (30.3)

0.933

NYHA class III and IV, n (%)3

468 (75.2)

250 (66.7)

218 (88.3)

<0.001

217 (64.8)

251 (87.5)

<0.001

Admission vital signs

       

SBP (mm Hg)3

113.2 ± 17.7

115.0 ± 31.1

118.7 ± 29.4

0.002

116.1 ± 17.6

109.7 ± 17.1

<0.001

DBP (mm Hg)3

72.2 ± 12.6

73.4 ± 12.1

70.4 ± 13.1

0.004

72.9 ± 12.2

71.4 ± 13.1

0.135

Heart rate, beat/min

80.5 ± 17.2

78.3 ± 16.2

83.9 ± 18.1

<0.001

78.7 ± 16.6

71.4 ± 13.1

0.004

Laboratory values at admission4

       

Glucose (mmol/L)

5.52 ± 1.66

5.44 ± 1.39

5.64 ± 1.99

0.154

5.57 ± 1.65

5.46 ± 1.66

0.425

TG (mmol/L)3

1.58 ± 0.90

1.68 ± 1.00

1.41 ± 0.69

<0.001

1.74 ± 0.94

1.38 ± 0.81

<0.001

TC (mmol/L)3

4.57 ± 1.11

4.68 ± 1.02

4.40 ± 1.22

0.004

4.84 ± 1.06

4.25 ± 1.09

<0.001

Creatinine (μmol/L)

92.3 ± 34.7

88.2 ± 29.9

98.4 ± 40.3

0.001

89.0 ± 28.5

96.1 ± 40.6

0.011

BUN (μmol/L)3

8.02 ± 4.09

7.89 ± 4.21

8.22 ± 3.89

0.328

7.96 ± 4.10

8.10 ± 4.07

0.666

NT Pro-BNP (pmol/mL)3

1652.85 (837.375-2907.2)

1367 (736.75-2259.4)

2281.5 (1218.1-3589.4)

<0.001

1089 (714.675-1949.1)

2529.05 (1439.1-3608.475)

<0.001

Electrocardiogram data2

       

QRS duration (ms)

119.2 ± 30.4

119.6 ± 31.1

118.7 ± 29.4

0.720

119.4 ± 30.2

119.0 ± 30.7

0.883

QT (ms)

407.7 ± 51.0

411.9 ± 50.5

401.2 ± 51.1

0.011

413.9 ± 49.6

400.4 ± 51.7

0.001

Echocardiography data4

       

LV (mm)3

68.3 ± 9.5

67.8 ± 9.5

69.3 ± 9.4

0.055

67.3 ± 8.9

69.5 ± 10.1

0.005

LVEF (mm)3

31.2 ± 8.5

32.2 ± 8.7

29.8 ± 7.9

0.001

33.0 ± 8.5

29.2 ± 7.9

<0.001

RV (mm)

24.2 ± 5.5

23.3 ± 5.0

25.5 ± 5.9

<0.001

22.6 ± 4.2

26.0 ± 6.1

<0.001

LA (mm)3

44.4 ± 7.8

43.1 ± 7.6

46.5 ± 7.8

<0.001

42.3 ± 7.2

46.9 ± 7.8

<0.001

Medicine at admission2

       

Diuretics, n (%)

589 (94.7)

352 (93.9)

237 (96.0)

0.080

314 (93.7)

275 (95.8)

0.048

ACEI/ARB, n (%)3

522 (83.9)

330 (88.0)

192 (77.7)

0.003

289 (86.3)

233 (81.2)

0.126

Beta-blockers, n (%)

564 (90.7)

349 (93.1)

215 (87.0)

0.038

306 (91.3)

258 (89.9)

0.857

Digoxin, n (%)

497 (79.9)

287 (76.5)

210 (85.0)

0.004

259 (77.3)

238 (82.9)

0.038

Aspirin/anticoagulation n (%)

393 (63.2)

237 (63.2)

156 (63.2)

0.868

211 (63.0)

182 (63.4)

0.725

Spironolactone, n (%)

572 (92.0)

347 (92.5)

225 (91.1)

0.837

306 (91.3)

266 (92.7)

0.193

  1. Note:
  2. 1Data are expressed as the mean ± SD, median (interquartile range) or percentage; P values are from an independent-samples t-test.
  3. 2Smoker was defined using standard questions about current smoking and lifetime smoking at least 100 cigarettes; drinkers who reported drinking 1 drink a day on average on days that they consumed alcohol during the previous year.
  4. 3 Abbreviations: NYHA New York Heart Association, SBP systolic blood pressure, DBP diastolic blood pressure, BUN blood urea nitrogen, TG triglycerides, TC total cholesterol, NT pro-BNP N-terminal fragment pro-brain natriuretic peptide, LV left ventricle, RV right ventricle, LA left atrium, LVEF left ventricular ejection fraction, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker.
  5. 4Ten patients lacked echocardiography data, 9 patients lacked electrocardiogram data, 4 patient lacked fasting blood glucose, 62 patients lacked NT-pro-BNP levels, 1 patient lacked creatinine, 2 patients lacked BUN levels, 5 patients lacked triglyceride, total cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol, 62 patients lacked NT pro-BNP levels, and 6 patients lacked medicines at admission.
  6. The bold data indicated that P<0.05.
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us