Table 2 Relationship between RYR3 polymorphisms and atherosclerosis severity >75%
From: Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population
Arteries | Ath (+/−) | rs877087 genotypes, n(%) | rs2229116 genotypes, n(%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TT | CT | CC | TT vs. CT + CC | AA | AG | GG | AA vs. AG + GG | ||||||
p a | OR(95% CI)b | p b | p a | OR(95% CI)b | p b | ||||||||
PAI | + | 319(96.4%) | 11(3.3%) | 1(0.3%) | 0.023 | 2.07 | 0.038 | 241(71.5%) | 84(24.9%) | 12(3.6%) | 0.008 | 1.38 | 0.035 |
(Total) | - | 840(93.2%) | 59(6.6%) | 2(0.2%) | (1.04–4.12) | 593(64.1%) | 292(31.6%) | 40(4.3%) | (1.02–1.86) | ||||
Common carotid | + | 666(94.7%) | 35(5.0%) | 2(0.3%) | 0.214 | 1.31 | 0.294 | 501(69.9%) | 190(26.5%) | 26(3.6%) | 0.003 | 1.45 | 0.003 |
- | 597(93.5%) | 40(6.3%) | 1(0.2%) | (0.79–2.15) | 412(62.7%) | 214(32.6%) | 31(4.7%) | (1.13–1.86) | |||||
(Total) | |||||||||||||
PAI | + | 183(96.3%) | 7(3.7%) | 0(0%) | 0.061 | 1.87 | 0.164 | 140(71.8%) | 47(24.1%) | 8(4.1%) | 0.042 | 1.58 | 0.026 |
(Male) | - | 440(92.8%) | 33(7.0%) | 1(0.2%) | (0.78–4.52) | 315(64.5%) | 153(31.4%) | 20(4.1%) | (1.06–2.38) | ||||
Common carotid | + | 381(94.1%) | 23(5.7%) | 1(0.2%) | 0.533 | 1.11 | 0.754 | 297(71.4%) | 103(24.8%) | 16(3.8%) | 0.005 | 1.63 | 0.004 |
- | 295(93.9%) | 19(6.1%) | 0(0%) | (0.57–2.16) | 201(62.0%) | 108(33.3%) | 15(4.7%) | (1.17–2.27) | |||||
(Male) | |||||||||||||
PAI | + | 136(96.5%) | 4(2.8%) | 1(0.7%) | 0.151 | 2.39 | 0.124 | 101(71.1%) | 37(26.1%) | 4(2.8%) | 0.062 | 1.23 | 0.374 |
(Female) | - | 400(93.7%) | 26(6.1%) | 1(0.2%) | (0.79–7.27) | 278(63.6%) | 139(31.8%) | 20(4.6%) | (0.78–1.93) | ||||
Common carotid | + | 285(95.6%) | 12(4.0%) | 1(0.3%) | 0.127 | 1.55 | 0.267 | 204(67.8%) | 87(28.9%) | 10(3.3%) | 0.139 | 1.25 | 0.234 |
- | 302(93.2%) | 21(6.5%) | 1(0.3%) | (0.72–3.37) | 211(63.4%) | 106(31.8%) | 16(4.8%) | (0.86–1.82) | |||||
(Female) | |||||||||||||