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Table 1 Expression of chemerin and CMKLR1 in periaortic adipose tissue, aortic VSMCs and atherosclerotic lesion foam cells in correlation with aortic atherosclerosis

From: Chemerin and CMKLR1 expression in human arteries and periadventitial fat: a possible role for local chemerin in atherosclerosis?

  

Aortic atherosclerosis

 
 

NO

I-II

III-IV

V-VI

 

Total

 

6

11

4

19

 

IHC score

 

n(%)

n(%)

n(%)

n(%)

r and p values

Periaortic fat chemerin expression

0

1(2.5)

2(5)

0(0)

0(0)

r=0.824, p < 0.001a

1

5(12.5)

5(12.5)

0(0)

0(0)

2

0(0)

4(10)

1(2.5)

4(10)

3

0(0)

0(0)

3(7.5)

15(37.5)

Aortic VSMC chemerin expression

0

0(0)

0(0)

0(0)

0(0)

r=0.626, p < 0.001a

1

3(7.5)

4(10)

1(2.5)

0(0)

2

3(7.5)

7(17.5)

1(2.5)

9(22.5)

3

0(0)

0(0)

2(5)

10(25)

Aortic foam cell chemerin expression

0

-b

7(20.6)

0(0)

0(0)

r=0.670, p < 0.001a

1

-

0(0)

0(0)

0(0)

2

-

1(2.9)

0(0)

1(2.9)

3

-

3(8.8)

4(11.8)

18(52.9)

Aortic VSMC CMKLR1 expression

0

6(15)

8(20)

3(7.5)

13(32.5)

r=0.189, p=0.243

1

0(0)

1(2.5)

1(2.5)

3(7.5)

2

0(0)

2(5)

0(0)

3(7.5)

3

0(0)

0(0)

0(0)

0(0)

Aortic foam cell CMKLR1 expression

0

-b

4(11.8)

0(0)

0(0)

r=0.424, p=0.012c

1

-

1(2.9)

2(5.9)

3(8.8)

2

-

4(11.8)

2(5.9)

7(20.6)

3

-

2(5.9)

0(0)

9(26.5)

  1. VSMC=vascular smooth muscle cell, IHC=Immunohistochemistry.
  2. aCorrelation is significant at the 0.01 level, bAbsence of foam cells in case of normal (non atherosclerotic) vessels, cCorrelation is significant at the 0.05 level.