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Table 3 Comparison of echocardiographic and clinical parameters between combined echocardiographic responders and non-responders at baseline

From: Predictors of positive response to cardiac resynchronization therapy

 

Responders (n = 62)

Non-responders (n = 14)

pvalue

LVEF (%)

21.2 ± 6.5

17.9 ± 5.4

0.09

LVEDD (mm)

66.8 ± 9.8

75.3 ± 6.5

0.01

LVESD (mm)

60.0 ± 10.0

68.4 ± 7.8

0.01

LVEDV (ml)

211.0 ± 77.6

255.4 ± 50.6

0.05

LVESV (ml)

166.4 ± 69.3

201 ± 53.5

0.09

LAV (ml)

89.1 ± 30.2

104.5 ± 17.6

0.02

QRS duration (ms)

174.5 ± 16.6

175.7 ± 19.6

0.89

Six minute walk test (m)

305.6 ± 71.5

307.7 ± 57.3

0.72

Age (yrs.)

63.2 ± 10.1

60.2 ± 11.4

0.32

Gender (male,%)

51 (81)

9 (69.2)

0.34

Paroxysmal AF n (%)

18 (28.6)

8 (61.5)

0.02

VT n (%)

16 (25.4)

7 (53.9)

0.04

CRT-D n (%)

25 (39.7)

8 (61.5)

0.15

Beta blockers n (%)

61 (96.8)

12 (92.3)

0.45

ACE-I n (%)

48 (76.2)

9 (69.2)

0.59

ARB n (%)

13 (20.6)

2 (15.4)

0.66

MRA n (%)

52 (82.5)

12 (92.3)

0.38

Diuretics n (%)

51 (81)

13 (100)

0.08

Amiodarone n (%)

16 (25.4)

5 (38.5)

0.33

Statin n (%)

33 (52.4)

6 (46.2)

0.68

Aspirin n (%)

23 (36.5)

4 (30.8)

0.69

Warfarin n (%)

16 (25.4)

8 (61.5)

0.01

Uric acid (μmol/l)

397.7 ± 111.5

506.3 ± 159.0

0.03

  1. LVEF – left ventricular ejection fraction, LVEDD – left ventricular end-diastolic diameter, LVESD - left ventricular end-systolic diameter, LVEDV - left ventricular end-diastolic volume, LVESV - left ventricular end-systolic volume, LAV – left atrial volume, AF – atrial fibrillation, VT- ventricular tachycardia, ACE-I – angiotensin converting enzyme inhibitors, ARB - angiotensin receptor blockers, MRA - mineralocorticoid receptor antagonists.
  2. p value for the comparison between responders and non-responders.