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Table 2 Hazard ratios for incident MACE adjusted for age and sex, according to early and late study periods among ConHD patients as compared with those without ConHD

From: Major adverse cardiovascular events in adult congenital heart disease: a population-based follow-up study from Taiwan

Event

ConHD

non-ConHD

Follow-up time

 

n/N

n/N

≥ 1.5 years

1.5 to 4 years

≥ 4 years

   

Adjusted HR (95% CI)

P value

 Adjusted HR (95% CI)

P value

Adjusted HR (95% CI)

P value

MACE

487/2919

336/6398

4.02

  (3.49, 4.62)

<.0001

5.50

  (4.32, 7.01)

<.0001

3.37

  (2.83, 4.02)

<.0001

ACS

72/3181

61/6413

2.89

  (2.05, 4.07)

<.0001

7.76

  (3.56, 16.93)

<.0001

2.06

  (1.37, 3.10)

0.0005

HF

337/3014

65/6412

13.20

  (10.11, 17.23)

<.0001

21.44

  (12.60, 36.48)

<.0001

10.61

  (7.76, 14.51)

<.0001

Stroke

214/3166

242/6402

2.16

  (1.79, 2.60)

<.0001

2.39

  (1.72, 3.31)

<.0001

2.06

  (1.64, 2.58)

<.0001

MD

48/3203

9/6412

12.57

  (6.15, 25.69)

<.0001

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  1. MACE, major adverse cardiovascular events; ConHD, congenital heart disease; ACS, acute coronary syndrome; HF, heart failure; MD, malignant dysrhythmia; N = total number of subjects; n = number of subjects with various; MACE; Adjusted HR (95% CI), hazard ratio for various incident MACEs (95% confidence interval) adjusted for age and sex.