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Table 3 Modification in lipid profile of dyslipidemic patients after simvastatin treatment by gender

From: Simvastatin down-regulates the production of Interleukin-8 by neutrophil leukocytes from dyslipidemic patients

 

Male (n = 7)

Female (n = 8)

 

Baseline

After treatment

Baseline

After treatment

Total cholesterol (mg/dl)

260 (236–316)

208 (172–263)

299 (278–347)

199 (176–229)*

LDL-cholesterol (mg/dl)

186 (172–207)

120 (99–160)+

207 (187–244)

118 (142–203)*

HDL-cholesterol (mg/dl)

50 (47–57)

54 (48–70)

51 (47–60)

52 (49–63)

Tryglicerides (mg/dl)

115 (87–134)

114 (83–167)

180 (142–203)

149 (95–153)

Apolipoprotein A (mg/dl)

141 (136–152)

136 (127–166)

145 (134–163)

147 (136–177)

Apolipoprotein B (mg/dl)

151 (139–168)

90 (85–126)+

180 (136–269)

101 (91–119)*

  1. *vs baseline (p = 0.001).
  2. +vs baseline (p = 0.05).