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Table 4 Subgroup analysis

From: Routine angiography in survivors of out of hospital cardiac arrest with return of spontaneous circulation: a single site registry

  Cathed (Group A) 63 patients Non-cathed (Group B) 15 patients p-value Good outcome (Group C) 53 patients Poor outcome (Group D) 25 patients p-value
Risk factors       
Age, mean(±SD) 61.1(14.1) 64.9(19.5) 0.20 59.4(14.9) 67.1(14.7) 0.01
Males, no. (%) 52(82.5) 11(73.3) 0.21 45(84.9) 18(72.0) 0.09
Diabetes, no. (%) [1]* 11(17.5) 2(14.3) 0.39 3(5.7) 10(41.7) <0.01
Hypertension, no. (%) [1] 32(50.8) 7(50.0) 0.48 27(50.9) 12(50.0) 0.46
Hyperlipidaemia, no. (%) [11] 25(46.3) 3(23.1) 0.07 19(41.3) 9(42.9) 0.45
History of IHD, no. (%) [2] 17(27.4) 3(21.4) 0.33 15(28.8) 5(20.8) 0.23
Serum creatinine μmol/L, median(IQR) 102(86–115) 125(113–161) <0.01 100(84–114) 119(107–142) <0.01
GFR ml/min, median(IQR) 63(52–78) 46(37–54) <0.01 66(55–81) 50(42–60) <0.01
History of smoking, no. (%) [19] 41(80.4) 6(75.0) 0.37 34(79.1) 13(81.3) 0.42
Peri cardiac arrest factors       
Time, min to first hospital, median(IQR) [16] 52(40–61) 70(51–80) <0.01 50(40–60) 63(50–73) 0.02
Time, hrs to TPCH, median(IQR) 3.9(1.0 -9.3) 4.0(1.9–6.9) 0.14 5.75(1.05–11.8) 1.25(1–4) <0.01
History of chest pain, no. (%) [3] 21(33.9) 4(30.8) 0.42 16(31.4) 9(37.5) 0.30
Time to ROSC in min, median(IQR) [11] 15(10–25) 22.5(15–29) 0.36 13.5(10–22.2) 20(15–35) 0.01
Treated at a peripheral hospital, no. (%) 35(55.6) 11(73.3) 0.12 35(66.0) 11(44.0) 0.03
ECG factors       
Initial rhythm VF/VT, no. (%) 56(88.9) 9(60.0) <0.01 47(88.7) 18(72.0) 0.03
ST elevation, no. (%) 30(47.6) 2(13.3) <0.01 21(39.6) 11(44.0) 0.36
QTc in milliseconds, mean(±SD) [2] 453(46) 464(51) 0.23 454(48.4) 457(43.4) 0.42
Assessments and tests       
GCS by paramedics, mean(±SD) [2] 5.4(4.7) 3.0(0) 0.03 5.84(5.06) 3.12(0.6) <0.01
CCF in ED, no. (%) 9(14.3) 2(13.3) 0.46 5(9.4) 6(24.0) 0.04
First measured LVEF, mean(±SD) [6] 37.7(17.2) 36.7(21.6) 0.43 39.2(18.2) 33.5(16.8) 0.11
Initial serum K mmol/L, mean(±SD) 3.9(0.7) 4.2(0.6) 0.06 3.9(0.7) 4.0(0.7) 0.20
Initial serum Mg mmol/l, mean(±SD) [5] 1.0(0.3) 1.0(0.5) 0.49 1.0(0.3) 1.1(0.6) 0.06
Peak CK in IU/L, median(IQR) [9] 1440(524–3562) 1810(1070–4050) 0.15 1440(544–3442) 1810(613–3870) 0.37
Peak Troponin I in μmol/L, median(IQR) [5] 20(4–71) 9(1–35) 0.20 15(5–56) 32(1–75) 0.42
Treatments       
Use of inotropes, no. (%) 27(42.9) 8(52.3) 0.24 20(37.7) 15(60.0) 0.03
Heparin/Enoxaparin, no. (%) [1] 59(93.7) 14(100) 0.34 51(96.2) 22(91.7) 0.21
Aspirin, no. (%) [1] 62(98.4) 11(78.6) <0.01 52(98.1) 21(87.5) 0.03
Clopidogrel, no. (%) [1] 50(79.4) 3(21.4) <0.01 37(69.8) 16(66.7) 0.39
Balloon pump, no. (%) 20(31.7) 2(13.3) 0.08 15(28.3) 7(28.0) 0.49
ICU stay in days, median(IQR) 4(2–6) 4(2–5.5) 0.36 4(2–6) 4(2–4) 0.15
Coronary angiogram at any time, no. (%) N/A N/A N/A 47(88.7) 16(64.0) <0.01
Initially presenting to TPCH     18 patients 14 patients  
Emergent coronary angiogram, no. (%)     11(61.1) 11(78.6) 0.15
Coronary angiogram at any time, no. (%)     16(88.9) 12(85.7) 0.40
Outcomes       
OOHCA caused by AMI, no. (%) 45(71.4) 6(40.0) 0.01    
Survived to discharge, no. (%) 47(74.6) 6(40.0) <0.01    
Neurological deficit, no. (%) 7(11.1) 0(0.0) 0.09    
Neurological deficit in survivors, no. (%) 7/47(14.9) 0/6(0.0) 0.16    
  1. *[n] Number of patients for whom information was missing is represented within square brackets.
  2. Group A = patients who had coronary angiogram (“cathed patients”).
  3. Group B = patients who did not have coronary angiography (“non-cathed patients”).
  4. Group C = patients who survived to discharge from hospital.
  5. Group D = patients who died during the hospital admission.