Figure 3From: Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification After 6 days of in vitro culture, VICs in collagen-deficient leaflets exhibited significantly higher levels of both proliferation and apoptosis. (A) Proliferating cells per total cell number on Day 6, and (B) Apoptotic cells per total cell number on Day 6, expressed as percent of no-enzyme control. *P <0.0005 compared to undepleted.Back to article page