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Figure 2 | BMC Cardiovascular Disorders

Figure 2

From: Phenotype, origin and estimated prevalence of a common long QT syndrome mutation: a clinical, genealogical and molecular genetics study including Swedish R518X/KCNQ1families

Figure 2

Overview of the chosen microsatellite markers used for haplotype analysis, including 14 microsatellite markers (nomenclature D11S- followed by the number under the arrows) flanking the KCNQ1 gene, spanning over a distance of ~8 cM (8 × 10 6 base pairs). The p.R518X mutation location in KCNQ1 is indicated by the vertical black line. Physical distances between the p.R518X mutation and each marker are given above. The grey arrowhead indicates the location of the D11S-1318 marker included in the p.Y111C haplotype analysis that was excluded in the current analysis due to a generally low quality of peaks and a high frequency of background noise.

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