Figure 5

Moderate endurance training (tr) helps normalize activity levels of enzymes implicated in the LV energy metabolism in 9-month AR rats. Indexed (i) heart weight was corrected for the tibial length. HADH (hydroxyacyl-Coenzyme A dehydrogenase), HK (hexokinase) PFK (phosphofructokinase), citrate synthase (CS) and complex 1 enzymatic activities were measured in LV homogenates as described in the Methods. Results are expressed as mean ± SEM (n = 10/group) in μmoles/min/mg of tissue. *p < 0.05, **p < 0.01 and ***p < 0.001 between sham and AR and ¶p < 0.05 between AR and AR-tr groups.