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Table 2 Association analysis of genetic polymorphisms with MI risk

From: Interaction of type 2 diabetes mellitus with Chromosome 9p21 rs10757274 polymorphism on the risk of myocardial infarction: a case–control study in Chinese population

Chromosome location Closest gene SNPs Genotypes Genotype frequencies (%) Without adjustment With adjustment
Controls (N = 308) MI patients (N = 502) OR (95% CI) p ORa(95% CI) p a
6P24 ADTRP rs6903956 GG 85.23 79.30 reference    
    GA 13.40 18.74 1.50 (1.00,2.27) 0.0525 1.55 (0.99,2.43) 0.0556
    AA 1.37 1.96 1.53 (0.47,5.03) 0.4813 1.04 (0.30,3.59) 0.9522
    AA/GA 14.78 20.70 1.51 (1.01,2.23) 0.0423 1.49(0.97,2.29) 0.0678
9P21 CDKN2A/B rs10757274 AA 32.78 23.54 reference    
    GA 51.32 52.52 1.43 (1.02,1.99) 0.0374 1.52(1.06,2.19) 0.0227
    GG 15.89 23.94 2.10 (1.37,3.22) 0.0007 2.40 (1.51,3.81) 0.0002
    GG/GA 67.22 76.46 1.58 (1.15,2.18) 0.0045 1.72 (1.22,2.43) 0.0020
  1. a: Adjusting for age, gender, ethnicity, BMI, smoking and drinking habits as covariates.