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Table 1 Characteristics of included studies

From: Glucose–insulin–potassium therapy in patients with acute coronary syndrome: a meta-analysis of randomized controlled trials

Study

No. of patients

Age*

Male(%)*

Killip I (%)*

Diabetes (%)*

Glucose (%)

Insulin (U/500 ml)

Potassium (%)

Infusion rate (ml/kg/h)

Time from onset of symptom to treatment (h)*

24-h glucose (mmol/L)*

ECLA (1998))

470

58.2/60.5

77/68.3

84.4/86.3

18.5/18

25

50

0.3

1.5

11.4/10.6

4.25/4.04

POL-GIK (1999)

954

62/60

70/67.2

94.1/97

6.5/6.1

10

32

0.3

42 ml/h

5

5.9/6.2

GIPS-I (2003)

940

59.9/60.8

73.7/79.3

89.5/92.7

10.5/10.6

20

7-11

0.3

3

2.75-2.78/2.75-2.82

7.7/8.1*

REVIAL (2004)

312

60.8/64.1

71.6/72.6

67.7/69.4

22.6/23.6

20

40

0.25

1.8

-

-

CREATE-ECLA (2005)

20201

58.6/58.6

77.6/77.6

84.2/85.1

17.6/17.8

25

50

0.3

1.5

4.7/4.7¶

8.6/7.5

Krljanac G (2005)

118

56.6/56.7

66.7/72.5

-

17/17

25

50

0.3

1

3.1/3.2

-

GIPS-II (2006)

889

61.8/61.2

73/74

100/100

9/10

20

 

0.3

2

-

-

OASIS-6 (2007)

2748

61.5/62.1

73.1/71.7

-

14.9/14.0

25

50

0.3

1.5

-

8.5/7.5

IMMEDIATE (2012)

871

63.9/63.3

72.5/69.6

-

29.4/26.3

30

25

0.6

1.5

1.5/1.5

-

  1. ECLA = Estudios Cardiologicos Latinoamerica; POL-GIK = Polish-Glucose-Insulin-Potassium; GIPS-I = Glucose–insulin–potassium study-I; GIPS-II = Glucose–insulin–potassium study-II; REVIVAL = The Reevaluation of Intensified Venous Metabolic Support for Acute Infarct Size Limitation; OASIS-6 = Organization to Assess Strategies for Ischemic Syndromes; DIGAMI = the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction; HI-5 = The hyperglycemia: intensive insulin infusion in infarction; IMMEDIATE = the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency care Trial.
  2. *numerator/denominator indicates treatment group/control group.
  3. ¶median, Glucose (%) and potassium (%) mass concentration.