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Table 4 Correlation between serum fibrosis biomarkers and collagen levels in the right and left atria of patients with atrial fibrillation

From: Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation

  

Fibrosis biomarker

 

Collagen I

Left atrium

PICP

PINP

  

r = 0.386, P = 0.001

r = 0.423, P = 0.003

 

Right atrium

PICP

TGF-β1

  

r = 0.336, P = 0.019

r = 0.258, P < 0.05

Collagen III

Left atrium

TGF-β1

PIIINP

  

r = 0.469, P < 0.001

r = 0.291, P = 0.042

 

Right atrium

Not significant

Not significant

  1. PICP, carboxyl-terminal peptide from pro-collagen I; PINP, N-terminal type I procollagen propeptides; PIIINP, N-terminal type III procollagen propeptides.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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