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Table 4 Correlation between serum fibrosis biomarkers and collagen levels in the right and left atria of patients with atrial fibrillation

From: Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl terminal peptide and TGF-β1 levels in serum of patients with atrial fibrillation

   Fibrosis biomarker  
Collagen I Left atrium PICP PINP
   r = 0.386, P = 0.001 r = 0.423, P = 0.003
  Right atrium PICP TGF-β1
   r = 0.336, P = 0.019 r = 0.258, P < 0.05
Collagen III Left atrium TGF-β1 PIIINP
   r = 0.469, P < 0.001 r = 0.291, P = 0.042
  Right atrium Not significant Not significant
  1. PICP, carboxyl-terminal peptide from pro-collagen I; PINP, N-terminal type I procollagen propeptides; PIIINP, N-terminal type III procollagen propeptides.