Figure 1
From: Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration
Ceramide inhibits left ventricle mitochondrial respiration. A: Respiration rates of mitochondria isolated from left ventricle myocardium with addition of C2-ceramide during respiration protocol (20 μM; n = 4). B: Mitochondrial respiration from permeabilized left ventricle myocardium (30 min) with continuous incubation with C2-ceramide (20 μM; n = 8). See Methods for more details on respiration protocol. *P <0.05.