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Table 3 Multivariable adjusted predictors of events (n = 3058)

From: Clinical course and outcomes of type-2 diabetic patients after treatment intensification for insufficient glycaemic control - results of the 2 year prospective DiaRegis follow-up

 

MAC/MIC/HF/Death OR (95% CI)

MAC* OR (95% CI)

MIC* OR (95% CI)

HF OR (95% CI)

Patient characteristics at baseline

    

 Age ≥ median

1.36 (1.10–1.68)

1.15 (0.71–1.86)

1.15 (0.89–1.47)

2.25 (1.21–4.16)

 Male vs. female

1.17 (0.96–1.43)

1.36 (0.87–2.14)

1.21 (0.96–1.54)

0.74 (0.45–1.20)

 BMI ≥ median

1.01 (0.83–1.23)

0.69 (0.45–1.07)

1.11 (0.87–1.41)

0.85 (0.52–1.38)

 Diabetes duration ≥ median

1.29 (1.06–1.57)

1.94 (1.24–3.05)

1.33 (1.05–1.68)

0.91 (0.56–1.48)

Laboratory values

    

 HbA1c ≥ median

1.12 (0.90–1.39)

0.92 (0.57–1.46)

1.29 (1.00–1.66)

1.14 (0.66–1.96)

 FPG ≥ median

1.09 (0.89–1.35)

1.00 (0.63–1.59)

1.18 (0.92–.51)

0.60 (0.34–1.04)

Complications

    

 Vascular disease*

1.73 (1.39–2.16)

2.72 (1.72–4.31)

1.58 (1.22–2.06)

1.14 (0.66–1.96)

 HF

2.78 (2.10–3.68)

1.97 (1.13–3.43)

1.53 (1.07–2.18)

--

 Severe hypoglycaemia

1.24 (0.59–2.62)

0.44 (0.06–3.38)

1.88 (0.85–4.14)

1.27 (0.35–4.60)

  1. Legend: MAC, macrovascular complication; MIC, microvascular complication; HF, heart failure; BMI, body mass index; FPG, fasting plasma glucose. *Vascular disease includes CAD, stroke/TIA, and PAD; MICs include previously unknown retinopathy, nephropathy, neuropathy, and amputation; MACs include MI, stroke/TIA, and PAD (any peripheral intervention). Bold ORs (95%CI) reflect significant predictors of events.