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Table 3 Multivariable adjusted predictors of events (n = 3058)

From: Clinical course and outcomes of type-2 diabetic patients after treatment intensification for insufficient glycaemic control - results of the 2 year prospective DiaRegis follow-up

  MAC/MIC/HF/Death OR (95% CI) MAC* OR (95% CI) MIC* OR (95% CI) HF OR (95% CI)
Patient characteristics at baseline     
 Age ≥ median 1.36 (1.10–1.68) 1.15 (0.71–1.86) 1.15 (0.89–1.47) 2.25 (1.21–4.16)
 Male vs. female 1.17 (0.96–1.43) 1.36 (0.87–2.14) 1.21 (0.96–1.54) 0.74 (0.45–1.20)
 BMI ≥ median 1.01 (0.83–1.23) 0.69 (0.45–1.07) 1.11 (0.87–1.41) 0.85 (0.52–1.38)
 Diabetes duration ≥ median 1.29 (1.06–1.57) 1.94 (1.24–3.05) 1.33 (1.05–1.68) 0.91 (0.56–1.48)
Laboratory values     
 HbA1c ≥ median 1.12 (0.90–1.39) 0.92 (0.57–1.46) 1.29 (1.00–1.66) 1.14 (0.66–1.96)
 FPG ≥ median 1.09 (0.89–1.35) 1.00 (0.63–1.59) 1.18 (0.92–.51) 0.60 (0.34–1.04)
Complications     
 Vascular disease* 1.73 (1.39–2.16) 2.72 (1.72–4.31) 1.58 (1.22–2.06) 1.14 (0.66–1.96)
 HF 2.78 (2.10–3.68) 1.97 (1.13–3.43) 1.53 (1.07–2.18) --
 Severe hypoglycaemia 1.24 (0.59–2.62) 0.44 (0.06–3.38) 1.88 (0.85–4.14) 1.27 (0.35–4.60)
  1. Legend: MAC, macrovascular complication; MIC, microvascular complication; HF, heart failure; BMI, body mass index; FPG, fasting plasma glucose. *Vascular disease includes CAD, stroke/TIA, and PAD; MICs include previously unknown retinopathy, nephropathy, neuropathy, and amputation; MACs include MI, stroke/TIA, and PAD (any peripheral intervention). Bold ORs (95%CI) reflect significant predictors of events.