Inclusion criteria | Exclusion criteria |
---|---|
- Signed informed consent | - Refused informed consent |
- eGFR between 15-45 ml/min | - Change of >5ml/min eGFR over the past 6 months |
- Change of <5ml/min in eGFR over the past 6 months | - Planned transplant within 6 months |
- Treated with maximal conventional CV disease risk reduction protocolized medications (ACEi or ARB) | - Likely to commence renal replacement therapy within 6 months after enrolment |
- Currently receiving vitamin D therapies, but agreeing to a washout period of 3 months | - Terminal malignancies |
 | - Active infections |
 | - Active inflammatory diseases (SLE, vasculitis) |