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Table 4 Immunohistochemistry analysis

From: I(f) current channel inhibitor (ivabradine) deserves cardioprotective effect via down-regulating the expression of matrix metalloproteinase (MMP)-2 and attenuating apoptosis in diabetic mice

  ivabradine (n = 6) Control (n = 6) P value
Matrix metalloproteinase-2    
  Staining score    
   Median (75% quartile)* 0.75 (1.00) 1.5 0(1.25) 0.048
   Mean (95%CI) 0.75 (0.29-0.92) 1.2 (0.64-1.76) 0.032
  Staining intensity, grade 1.9 ± 0.3 3.9 ± 0.3 0.022
   Week + moderate, n(%) 4 (66) 1 (17) 0.043
   Strong + very strong, n(%) 2 (14) 5 (83) 0.043
  1. *Non-normal data distribution. Nonparametric analysis was used for the comparison between the two groups.