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Table 4 Immunohistochemistry analysis

From: I(f) current channel inhibitor (ivabradine) deserves cardioprotective effect via down-regulating the expression of matrix metalloproteinase (MMP)-2 and attenuating apoptosis in diabetic mice

 

ivabradine (n = 6)

Control (n = 6)

P value

Matrix metalloproteinase-2

   

  Staining score

   

   Median (75% quartile)*

0.75 (1.00)

1.5 0(1.25)

0.048

   Mean (95%CI)

0.75 (0.29-0.92)

1.2 (0.64-1.76)

0.032

  Staining intensity, grade

1.9 ± 0.3

3.9 ± 0.3

0.022

   Week + moderate, n(%)

4 (66)

1 (17)

0.043

   Strong + very strong, n(%)

2 (14)

5 (83)

0.043

  1. *Non-normal data distribution. Nonparametric analysis was used for the comparison between the two groups.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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