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Table 3 crude and adjusted hazard ratio of covariates associated with 1-year mortality in Cox regression analysis

From: Impact of renal insufficiency on mortality in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

 

Valid cases

Crude hazard ratio (95% CI)

Pvalue

Adjusted hazard ratio (95% CI)

Pvalue

Male gender

4,116

0.68 (0.56-0.83)

<0.001

1.11 (0.88-1.41)

0.354

Creatinine clearance

4,116

 

<0.001

 

<0.001

   Creatinine clearance ≥ 60 mL/min

 

Reference

 

Reference

 

   Creatinine clearance ≤30 < 60 mL/min

 

5.31 (4.35-6.49)

 

2.71 (2.09-3.51)

 

   Creatinie clearance < 30 mL/min

 

15.37 (11.27-21.04)

 

7.09 (4.82-10.44)

 

Age – years

4,116

1.07 (1.06-1.08)

<0.001

1.04 (1.03-1.06)

<0.001

Diabetes mellitus

4,116

2.47 (1.95-3.13)

<0.001

1.77 (1.33-2.35)

<0.001

Hypertension

4,047

1.26 (1.03-1.53)

0.025

1.40 (1.11-1.76)

0.004

Previous myocardial infarction

4,043

1.99 (1.57-2.53)

<0.001

1.53 (1.14-2.07)

0.006

Glycoprotein IIb/IIIa receptor blocker

3,826

0.49 (0.40-0.61)

<0.001

0.68 (0.53-0.86)

<0.001

Multivessel disease

4,011

2.32 (1.91-2.83)

<0.001

1.15 (0.90-1.46)

0.265

Infarct related artery

4,011

 

<0.001

 

0.023

   Right coronary artery

 

Reference

 

Reference

 

   Left anterior descending artery

 

1.19 (0.96-1.48)

 

1.31 (1.03-1.68)

 

   Left circumflex artery

 

1.02 (0.74-1.40)

 

1.24 (0.88-1.74)

 

   Left main

 

4.02 (2.73-5.92)

 

1.92 (1.20-3.08)

 

Killip class

4,030

 

<0.001

 

<0.001

   I

 

Reference

 

Reference

 

   II

 

2.32 (1.64-3.30)

 

1.20 (1.20-2.69)

 

   III

 

4.54 (3.17-6.51)

 

1.68 (1.68-3.79)

 

   IV

 

9.55 (7.32-12.46)

 

1.86 (2.86-5.75)

 

Duration of procedure - minutes

4,100

1.01 (1.01-1.02)

<0.001

1.01 (1.00-1.01)

0.007