Table 1 Baseline clinical characteristics according to kidney function
|  | CrCl ≥ 60 | Valid cases | CrCl < 60 | Valid cases | Pvalue (CrCl ≥ 60 vs. CrCl < 60) | CrCl ≤30 < 60 | CrCl < 30 | Pvalue (CrCl < 30 vs. CrCl ≤30 < 60) |
|---|---|---|---|---|---|---|---|---|
Number of patients - no. | 3,218 | 3,218 | 898 | 898 | Â | 810 | 88 | Â |
Male gender - no. (%) | 2,486 (77.3) | 3,218 | 524 (58.4) | 898 | <0.001 | 471 (58.1) | 53 (60.2) | 0.707 |
Age – (year) | 61.5 ± 12.1 | 3,218 | 73.5 ± 11.0 | 898 | <0.001 | 73.5 ± 10.8 | 72.8 ± 12.8 | 0.532 |
Family history - no. (%) | 1,235 (39.8) | 3103 | 194 (23.5) | 824 | <0.001 | 178 (23.8) | 16 (20.8) | 0.548 |
Smoking - no. (%) | 1,712 (57.2) | 2991 | 290 (39.1) | 741 | <0.001 | 257 (38.1) | 33 (49.3) | 0.075 |
Body Mass Index – (kg/m2) | 26.8 (4.4) | 2,132 | 26.6 (4.6) | 507 | 0.256 | 26.7 (4.6) | 24.9 (4.2) | 0.009 |
Diabetes - no. (%) | 272 (8.5) | 3218 | 120 (13.4) | 898 | <0.001 | 101 (12.5) | 19 (21.6) | 0.017 |
Hypertension - no. (%) | 930 (29.2) | 3,180 | 404 (46.6) | 867 | <0.001 | 358 (45.8) | 46 (54.1) | 0.143 |
Previous coronary artery bypass grafting - no. (%) | 64 (2.0) | 3,214 | 23 (2.6) | 893 | 0.283 | 21 (2.6) | 2 (2.3) | 1.000 |
Previous percutaneous coronary intervention - no. (%) | 203 (6.4) | 3,164 | 58 (6.7) | 868 | 0.778 | 48 (6.1) | 10 (11.8) | 0.048 |
Previous myocardial infarction - no. (%) | 330 (10.4) | 3,168 | 127 (14.5) | 875 | 0.001 | 108 (13.7) | 19 (13.7) | 0.31 |
Lipid lowering therapy - no. (%) | 617 (19.4) | 3,173 | 201 (23.2) | 866 | 0.015 | 173 (22.2) | 28 (32.9) | 0.025 |
Glycoprotein IIb/IIIa receptor blocker – no. (%) | 1,445 (48.2) | 2,998 | 285 (34.4) | 828 | <0.001 | 263 (35.8) | 22 (26.5) | 0.110 |
Systolic blood pressure - (mmHg) | 122.9 ±24.9 | 2,467 | 118.1 ±30.5 | 662 | <0.001 | 118.7 ±30.3 | 112.4 ±32.0 | 0.118 |
Diastolic blood pressure - (mmHg) | 71.8 ±13.9 | 2,449 | 66.0 ± 15.1 | 654 | <0.001 | 66.4 ± 15.1 | 62.3 ± 15.9 | 0.043 |