Comparison of clinical outcomes in patients undergoing mitral valve replacement with mechanical or biological substitutes: a 20 years cohort

Table 4 Predictors of death by Cox regression analysis

Variable	HR (95% CI)	p
Mechanical prosthesis	0.96 (0.61-1.50)	0.855
Renal failure	4.41 (2.36-8.25)	< 0.001
Bleeding events	3.13 (1.68-5.80)	< 0.001
Age group
≤ 50 years	1.0
51–60 years	1.39 (0.82-2.38)	0.224
61–70 years	1.98 (1.11-3.56)	0.022
≥ 71 years	2.96 (1.54-5.71)	0.001
Mitral regurgitation	1.49 (0.97-2.29)	0.069
SAH	1.45 (0.95-2.23)	0.088
Chronic atrial fibrillation	1.46 (0.91-2.33)	0.114
Emergency surgery	1.69 (0.82-3.47)	0.153
Diabetes mellitus	1.62 (0.82-3.19)	0.163
Ischemia time	1.01 (0.99-1.01)	0.180
ICU time (h)	1.00 (0.99-1.00)	0.492
Hospitalization time	1.01 (0.99-1.02)	0.501
MV time (h)	1.00 (1.00-1.01)	0.589
Diameter	1.03 (0.92-1.15)	0.654
CHF class III and IV	1.10 (0.70-1.75)	0.675
Postoperative stroke	1.36 (0.31-5.99)	0.681
COPD	0.91 (0.48-1.70)	0.759
ECC time > 120 min	1.11 (0.40-3.10)	0.843
Rheumatic fever	1.02 (0.60-1.71)	0.949

HR, hazard ratio; 95% CI = 95% confidence interval; BMI, body mass index;
ECC, extracorporeal circulation; ICU, intensive care unit; MV, mechanical ventilation; CHF, congestive heart failure; AMI, acute myocardial infarction; COPD, chronic obstructive pulmonary disease; SAH, systemic arterial hypertension.
Significant results (p < 0.005) are highlighted in bold.

ISSN: 1471-2261