Figure 6
From: BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection
Overexpression of BRG1 increases MMP2 and MMP9 expression in aortic SMCs. Aortic SMCs were infected with Ad.BRG1 (or Ad.Null) at a MOI of 100. The expression of MMP2 and MMP9 were detected at 72 hr post-infection by qRT-PCR and western blot and normalized to that of GAPDH and β-actin, respectively. Histogram showed the expression level of MMP2 and MMP9 at the mRNA (A) and protein (B) level in Ad.BRG1-infected and Ad.Null-infected aortic SMCs. Data represent mean ± SEM from 4 independent experiments; **, P <0.01 by t test.