Overexpression of BRG1 increases MMP2 and MMP9 expression in aortic SMCs. Aortic SMCs were infected with Ad.BRG1 (or Ad.Null) at a MOI of 100. The expression of MMP2 and MMP9 were detected at 72 hr post-infection by qRT-PCR and western blot and normalized to that of GAPDH and β-actin, respectively. Histogram showed the expression level of MMP2 and MMP9 at the mRNA (A) and protein (B) level in Ad.BRG1-infected and Ad.Null-infected aortic SMCs. Data represent mean ± SEM from 4 independent experiments; **, P <0.01 by t test.