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Table 2 M-mode parameters of the LV (parasternal short-axis view) in control and db/db mice

From: Speckle tracking echocardiography in the diagnosis of early left ventricular systolic dysfunction in type II diabetic mice

Variables

Control

Db/db

Pvalue

8 weeks

   

Heart Rate(bmp)

397.50 ± 25.46

378.22 ± 37.25

P > 0.05

IVST(mm)

0.71 ± 0.05

0.66 ± 0.05

P > 0.05

LVPWD(mm)

0.69 ± 0.06

0.68 ± 0.05

P > 0.05

LVEDD(mm)

3.79 ± 0.23

3.68 ± 0.28

P > 0.05

LVESD(mm)

2.41 ± 0.27

2.26 ± 0.23

P > 0.05

LVEF(%)

66.25 ± 7.43

69.15 ± 7.25

P > 0.05

LVFS(%)

36.44 ± 5.13

38.39 ± 5.58

P > 0.05

LV mass(mg)

90.39 ± 11.15

83.32 ± 10.89

P > 0.05

12 weeks

   

Heart Rate(bmp)

392.50 ± 44.99

388.77 ± 39.02

P > 0.05

IVST(mm)

0.68 ± 0.06

0.71 ± 0.05

P > 0.05

LVPWD(mm)

0.70 ± 0.06

0.69 ± 0.06

P > 0.05

LVEDD(mm)

3.90 ± 0.26

3.82 ± 0.18

P > 0.05

LVESD(mm)

2.49 ± 0.31

2.37 ± 0.20

P > 0.05

LVEF(%)

65.91 ± 7.54

68.51 ± 5.25

P > 0.05

LVFS(%)

36.01 ± 5.38

37.99 ± 4.53

P > 0.05

LV mass(mg)

93.21 ± 9.52

92.24 ± 13.44

P > 0.05

16 weeks

   

Heart Rate(bmp)

381.25 ± 21.94

391.44 ± 39.81

P > 0.05

IVST(mm)

0.72 ± 0.03

0.71 ± 0.03

P > 0.05

LVPWD(mm)

0.69 ± 0.04

0.69 ± 0.05

P > 0.05

LVEDD(mm)

3.94 ± 0.19

3.77 ± 0.35

P > 0.05

LVESD(mm)

2.53 ± 0.21

2.36 ± 0.28

P > 0.05

LVEF(%)

66.78 ± 4.17

67.55 ± 7.79

P > 0.05

LVFS(%)

36.57 ± 3.30

37.25 ± 6.05

P > 0.05

LV mass(mg)

97.81 ± 8.31

90.98 ± 14.37

P > 0.05

  1. The diagram shows no significant difference in the measurements of heart rate, left ventricular dimensions, thickness and function parameters by M-mode echocardiography in dbdb and control mice at 8,12 and 16 weeks of age (P > 0.05).