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Table 2 M-mode parameters of the LV (parasternal short-axis view) in control and db/db mice

From: Speckle tracking echocardiography in the diagnosis of early left ventricular systolic dysfunction in type II diabetic mice

Variables Control Db/db Pvalue
8 weeks    
Heart Rate(bmp) 397.50 ± 25.46 378.22 ± 37.25 P > 0.05
IVST(mm) 0.71 ± 0.05 0.66 ± 0.05 P > 0.05
LVPWD(mm) 0.69 ± 0.06 0.68 ± 0.05 P > 0.05
LVEDD(mm) 3.79 ± 0.23 3.68 ± 0.28 P > 0.05
LVESD(mm) 2.41 ± 0.27 2.26 ± 0.23 P > 0.05
LVEF(%) 66.25 ± 7.43 69.15 ± 7.25 P > 0.05
LVFS(%) 36.44 ± 5.13 38.39 ± 5.58 P > 0.05
LV mass(mg) 90.39 ± 11.15 83.32 ± 10.89 P > 0.05
12 weeks    
Heart Rate(bmp) 392.50 ± 44.99 388.77 ± 39.02 P > 0.05
IVST(mm) 0.68 ± 0.06 0.71 ± 0.05 P > 0.05
LVPWD(mm) 0.70 ± 0.06 0.69 ± 0.06 P > 0.05
LVEDD(mm) 3.90 ± 0.26 3.82 ± 0.18 P > 0.05
LVESD(mm) 2.49 ± 0.31 2.37 ± 0.20 P > 0.05
LVEF(%) 65.91 ± 7.54 68.51 ± 5.25 P > 0.05
LVFS(%) 36.01 ± 5.38 37.99 ± 4.53 P > 0.05
LV mass(mg) 93.21 ± 9.52 92.24 ± 13.44 P > 0.05
16 weeks    
Heart Rate(bmp) 381.25 ± 21.94 391.44 ± 39.81 P > 0.05
IVST(mm) 0.72 ± 0.03 0.71 ± 0.03 P > 0.05
LVPWD(mm) 0.69 ± 0.04 0.69 ± 0.05 P > 0.05
LVEDD(mm) 3.94 ± 0.19 3.77 ± 0.35 P > 0.05
LVESD(mm) 2.53 ± 0.21 2.36 ± 0.28 P > 0.05
LVEF(%) 66.78 ± 4.17 67.55 ± 7.79 P > 0.05
LVFS(%) 36.57 ± 3.30 37.25 ± 6.05 P > 0.05
LV mass(mg) 97.81 ± 8.31 90.98 ± 14.37 P > 0.05
  1. The diagram shows no significant difference in the measurements of heart rate, left ventricular dimensions, thickness and function parameters by M-mode echocardiography in dbdb and control mice at 8,12 and 16 weeks of age (P > 0.05).