Speckle tracking echocardiography in the diagnosis of early left ventricular systolic dysfunction in type II diabetic mice

Table 1 Characteristics of control and db/db mice

Variables	Control	Db/db	Pvalue
8 weeks
Body Weight (g)	22.26 ± 1.08	40.19 ± 1.96	P < 0.0001
Heart Weight (g)	0.12 ± 0.01	0.12 ± 0.01	P > 0.05
HW/BW	0.005 ± 0.0009	0.003 ± 0.0004	P < 0.0001
fasting blood glucose(mmol/L)	2.52 ± 0.50	7.62 ± 1.15	P < 0.0001
12 weeks
Body Weight (g)	25.71 ± 1.41	47.82 ± 2.67	P < 0.0001
Heart Weight (g)	0.13 ± 0.01	0.13 ± 0.01	P > 0.05
HW/BW	0.005 ± 0.0002	0.003 ± 0.0002	P < 0.0001
fasting blood glucose(mmol/L)	2.15 ± 0.57	8.12 ± 1.22	P < 0.0001
16 weeks
Body Weight (g)	27.14 ± 1.95	43.42 ± 2.05	P < 0.0001
Heart Weight (g)	0.13 ± 0.02	0.12 ± 0.01	P > 0.05
HW/BW	0.005 ± 0.0006	0.002 ± 0.0002	P < 0.0001
fasting blood glucose(mmol/L)	2.66 ± 0.29	12.71 ± 2.47	P < 0.0001

The table shows the diabetic mice have larger body weight and fasting blood glucose compared to control mice at 8, 12 or 16 weeks of age.

ISSN: 1471-2261