Table 4 Adjusted hazard ratios for cardiovascular outcomes within all covariables include in the final multivariable models

Age (years)

1.08 (1.06–1.10)

<0.001

1.04 (1.00–1.07)

0.034

1.09 (1.05–1.12)

<0.001

1.15 (1.11–1.19)

<0.001

Type of Mediterranean diet

  With extra-Virgin Olive oil

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

  With mixed nuts

0.97 (0.74–1.35)

0.984

0.98 (0.60–1.60)

0.938

0.76 (0.49–1.22)

0.277

1.37 (0.80–2.34)

0.255

  Low fat diet

1.42 (1.07–1.88)

0.014

1.35 (0.84–2.15)

0.205

1.44 (0.98–2.12)

0.062

1.38 (0.80–2.38)

0.242

High alcohol consumption

0.85 (0.63–1.15)

0.292

0.59 (0.35–1.00)

0.052

1.17 (0.77–1.77)

0.472

0.98 (0.58–1.66)

0.949

Smoking status

  Never smoked

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

  Former smoker

1.45 (1–04–2.03)

0.031

1.47 (0.84–2.56)

0.176

1.14 (0.69–1.86)

0.615

2.27 (1.22- 4.24)

0.010

  Current-smoker

1.94 (1–33–2.84)

0.001

2.18 (1.20–3.97)

0.011

1.46 (0.82–2.58)

0.197

2.51 (1.20–5.22)

0.014

Body-mass index (Kg/m²)

1.01 (0.97–1.04)

0.661

1.01 (0.96–1.07)

0.697

1.00 (0.95–1.04)

0.875

1.03 (0.96–1.09)

0.421

Hypertension

1.79 (1.06–3.02)

0.030

1.53 (0.70–3.32)

0.284

2.19 (0.96–4.99)

0.063

2.22 (0.69–7.08)

0.179

Type 2 diabetes

1.30 (0.98–1.74)

0.071

1.23 (0.78–1.96)

0.374

1.53 (1.00–2.35)

0.052

1.21 (0.71–2.05)

0.477

Dyslipidaemia

0.91 (0.70–1.18)

0.468

0.82 (0.54–1.26)

0.376

0.94 (0.64–1.38)

0.762

0.89 (0.55–1.44)

0.630

Family history of premature CHD^§

1.24 (0.92–1.68)

0.155

1.56 (0.98–2.48)

0.060

1.25 (0.82–1.91)

0.304

0.70 (0.34–1.40)

0.313