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Table 2 Incidence and adjusted hazard ratios for cardiovascular events according to psychosocial factors

From: Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study

 

Educational level*

Social support in the household

Diagnosis of depression

 

High education

Low education

Live with other

Live alone

No

Yes

 

(N = 1646)

(N = 5617)

(N = 6535)

(N = 728)

(N = 5954)

(N = 1309)

Person-year of follow-up

7069,0

24280,89

28287,36

3062,56

25751,12

5598,79

Composite primary cardiovascular event

      

  Number of events

56

224

257

23

248

32

  Crude Rate/1000 person-year (95% CI)

7.9 (5.8–10.0)

9.2 (8.0–10.4)

9.1 (8.0–10.2)

7.5 (4.4–10.6)

9.6 (8.4–10.8)

5.7 (3.7–7.7)

  Adjusted Hazard Ratio (95% CI)†‡

1.00 (ref)

1.16 (0.85–1.57)

1.00 (ref)

0.85 (0.54–1.32)

1.00 (ref)

0.76 (0.52–1.11)

  p-value

 

0.351

 

0.458

 

0.155

Myocardial Infarction

      

  Number of events

24

79

95

8

90

13

  Crude Rate/1000 person-year (95% CI)

3.4 (2.0–4.8)

3.3 (2.5–4.0)

3.4 (2.7–4.0)

2.6 (0.8–4.4)

3.5 (2.8–4.2)

2.3 (1.1–3.6)

  Adjusted Hazard Ratio (95% CI)†‡

1.00 (ref)

1.10 (0.69–1.78)

1.00 (ref)

1.01 (0.48–2.12)

1.00 (ref)

0.89 (0.49–1.62)

  p-value

 

0.686

 

0.980

 

0.699

Stroke

      

  Number of events

17

119

127

9

121

15

  Crude Rate/1000 person-year (95% CI)

2.4 (1.3–3.5)

4.9 (4.0–5.8)

4.5 (3.7–5.3)

2.9 (1.0–4.9)

4.7 (3.9–5.5)

2.7 (1.3–4.0)

  Adjusted Hazard Ratio (95% CI)†‡

1.00 (ref)

1.83 (1.09–3.09)

1.00 (ref)

0.56 (0.28–1.12)

1.00 (ref)

0.66 (0.38–1.15)

  p-value

 

0.023

 

0.102

 

0.145

Cardiovascular Death

      

  Number of events

25

58

73

10

73

10

  Crude Rate/1000 person-year (95% CI)

3.5 (2.2–4.9)

2.4 (1.8–3.0)

2.6 (2.0–3.2)

3.3 (1.2–5.3)

2.8 (2.2–3.5)

1.8 (0.7–2.9)

  Adjusted Hazard Ratio (95% CI)†‡

1.00 (ref)

0.63 (0.38–1.03)

1.00 (ref)

1.21 (0.60–2.46)

1.00 (ref)

0.93 (0.47–1.84)

  p-value

 

0.064

 

0.598

 

0.832

  1. *High education means university studies or secondary school; Low education: up to primary studies.
  2. †Multivariable models were adjusted by: age, gender, smoking, alcohol consumption, body-mass index, hypertension, type 2 diabetes, dyslipidemia and family history of premature coronary heart disease, and type Mediterranean diet intervention.
  3. ‡Test of proportional-hazard assumption (p-value based on the scaled Schoenfeld residuals): Composite primary cardiovascular event model (specific p-value for Educational level: 0.529, Social support: 0.765 and Depression: 0.877); Myocardial infarction model (0.611, 0.717 and 0.914); Stroke model (p-values = 0.204, 0.598 and 0.411); Cardiovascular death model (p-values = 0.810, 0.831 and 0.129).
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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