Skip to main content

Table 1 Socio-demographic and clinical characteristics of participants with limiting dyspnoea (n = 155)*

From: Utility of NT-proBNP as a rule-out test for left ventricular dysfunction in very old people with limiting dyspnoea: the Newcastle 85+ Study

Age, mean (SD); range 88.0 (0.5); 87.0-88.9
Female 65.8 (102)
Ethnic origin- white 100 (155)
Institutional care 2.6 (4)
Heart failure 13.6 (21)
Hypertension 54.2 (84)
Ischaemic heart disease 40.0 (62)
Myocardial infarction 21.9 (34)
Cerebrovascular disease 20.0 (31)
Peripheral vascular disease 3.2 (5)
Atrial fibrillation 24.5 (38)
Diabetes Mellitus 10.3 (16)
Severe renal impairment (estimated glomerular filtration rate <30 ml/min/1.73 m2) 3.2 (5)
Cognitive impairment (mini-mental state examination score ≤21) 3.9 (6)
Number of chronic diseases, median (IQR) 5 (4-6)
Smoking Status  
   Current smoker 5.2 (8)
   Former regular smoker 56.5 (87)
   Former occasional smoker 4.6 (7)
   Never smoked 33.8 (52)
Obese (BMI >30 kg/m2) 11.0 (17)
On any prescribed cardiac medications 69.7 (108)
Number of prescribed cardiovascular medications, median (IQR) 1 (0-2)
Echocardiographically-characterised LV dysfunction  
   Any grade of systolic dysfunction (LVEF≤50%) 34.2 (53)
   Moderate/severe systolic dysfunction (LVEF≤40%) 8.4 (13)
   Any grade of diastolic dysfunction 87.7 (136)
   Moderate/severe diastolic dysfunction 30.3 (47)
   Isolated diastolic dysfunction, any grade 58.7 (91)
   Isolated moderate/severe diastolic dysfunction 19.4 (30)
NT-ProBNP, median (IQR); range (ng/l) 406 (197-1068); 37-12360
  1. *All data are %(n) except where indicated; denominators may vary due to missing values.
  2. 18 diseases considered: hypertension, ischaemic heart disease, cerebrovascular disease, peripheral vascular disease, heart failure, atrial flutter or fibrillation, arthritis, osteoporosis, chronic obstructive pulmonary disease or asthma, other respiratory disease, diabetes mellitus, hypothyroidism or hyperthyroidism, cancer diagnosed within past 5 years (excluding non-melanoma skin cancer), eye disease, dementia, Parkinson's Disease, renal impairment and anaemia.