Figure 8

The high fat diet impact on myocardial mitochondria. HK (A; hexokinase), complex 1 (B) and SDH (C; succinate dehydrogenase) enzymatic activities were measured as described in the Materials and Methods. Evaluation by real-time quantitative RT-PCR of the LV mRNA levels of ANT1 (adenine nucleotide translocator-1) and UCP-3 (uncoupling protein-3) is illustrated in Panel D. **: p < 0.01 and ***: p < 0.001 between sham and AR groups. §: p < 0.05 and §§§: p < 0.001 vs. corresponding sham or AR group.