Effects of reduced β
GP I on aortic MMP2, MMP9, TIMP-1, and TIMP-2 mRNA expression levels. Aorta was sampled at day 22 (mono-dose groups) and day 43 (complex-dose groups) with ten aortas selected from each group after treatment and then assessed by real time PCR. GADPH was selected as the internal control. A. MMP2. B. MMP9. C. TIMP-2. D. TIMP-1. E. MMP2/TIMP-2. F. MMP9/TIMP-1. *
P < 0.05 vs. normal controls; #
P < 0.05 vs. diabetic controls; @
P < 0.05 vs. reduced β2GP I (R-β2GP I); and &P < 0.05 vs. β2GP I.