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Table 2 Hazard ratios for fasting plasma insulin in relation to incidence of AF

From: Low fasting plasma insulin is associated with atrial fibrillation in men from a cohort study - the Malmö preventive project

   Model 1 Model 2
   HR 95% CI P HR 95% CI P
Both genders Ln-Insulin 0.82 0.75-0.90 <.0001 0.81 0.74.0.88 <.0001
Quartile 1 reference      
Quartile 2 0.95 0.80-1.11 0.54 0.95 0.80-1.13 0.54
Quartile 3 0.75 0.62-0.90 0.002 0.74 0.62-0.89 0.002
Quartile 4 0.71 0.59-0.86 <.0001 0.69 0.57-0.84 <.0001
Men Ln-Insulin 0.81 0.73-0.89 <.0001 0.79 0.72-0.87 <.0001
Quartile 1 reference      
Quartile 2 0.90 0.75-1.08 0.28 0.91 0.76-1.08 0.28
Quartile 3 0.72 0.59-0.88 0.001 0.71 0.58-0.86 0.001
Quartile 4 0.66 0.54-0.81 <.0001 0.64 0.52-0.78 <.0001
Women Ln-Insulin 0.98 0.74-1.31 0.91 0.97 0.72-1.30 0.86
Quartile 1 reference      
Quartile 2 1.24 0.68-2.29 0.48 1.21 0.66-2.22 0.55
Quartile 3 0.94 0.56-1.57 0.82 0.95 0.57-1.59 0.85
Quartile 4 1.18 0.71-1.96 0.52 1.16 0.69-1.93 0.58
  1. Based on 7066 individuals (6052 men and 1014 women) and 983 cases. Model 1 is adjusted for age, sex (where applicable), height and weight. Model 2 is adjusted for Model 1 covariates + systolic blood pressure and smoking status. HR for Ln-insulin is expressed per 1 log unit.