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Table 2 Hazard ratios for fasting plasma insulin in relation to incidence of AF

From: Low fasting plasma insulin is associated with atrial fibrillation in men from a cohort study - the Malmö preventive project

  

Model 1

Model 2

  

HR

95% CI

P

HR

95% CI

P

Both genders

Ln-Insulin

0.82

0.75-0.90

<.0001

0.81

0.74.0.88

<.0001

Quartile 1

reference

     

Quartile 2

0.95

0.80-1.11

0.54

0.95

0.80-1.13

0.54

Quartile 3

0.75

0.62-0.90

0.002

0.74

0.62-0.89

0.002

Quartile 4

0.71

0.59-0.86

<.0001

0.69

0.57-0.84

<.0001

Men

Ln-Insulin

0.81

0.73-0.89

<.0001

0.79

0.72-0.87

<.0001

Quartile 1

reference

     

Quartile 2

0.90

0.75-1.08

0.28

0.91

0.76-1.08

0.28

Quartile 3

0.72

0.59-0.88

0.001

0.71

0.58-0.86

0.001

Quartile 4

0.66

0.54-0.81

<.0001

0.64

0.52-0.78

<.0001

Women

Ln-Insulin

0.98

0.74-1.31

0.91

0.97

0.72-1.30

0.86

Quartile 1

reference

     

Quartile 2

1.24

0.68-2.29

0.48

1.21

0.66-2.22

0.55

Quartile 3

0.94

0.56-1.57

0.82

0.95

0.57-1.59

0.85

Quartile 4

1.18

0.71-1.96

0.52

1.16

0.69-1.93

0.58

  1. Based on 7066 individuals (6052 men and 1014 women) and 983 cases. Model 1 is adjusted for age, sex (where applicable), height and weight. Model 2 is adjusted for Model 1 covariates + systolic blood pressure and smoking status. HR for Ln-insulin is expressed per 1 log unit.