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Table 1 Baseline characteristics

From: Differential association between metabolic syndrome and coronary artery disease evaluated with cardiac computed tomography according to the presence of diabetes in a symptomatic Korean population

Characteristics

No diabetes

P

Type 2 diabetes

P

 

Total

No MetS

MetS

 

Total

No MetS

MetS

 
 

(n = 2,308)

(n = 1,515)

(n = 793)

 

(n = 561)

(n = 176)

(n = 385)

 

Subjects

        

Age (years)

57 ± 9

57 ± 9

57 ± 9

0.526

60 ± 9*

61 ± 9

60 ± 8

0.219

Men, n (%)

1,155 (50)

749 (49)

406 (51)

0.430

313 (56)†

105 (60)

208 (54)

0.234

Body mass index (kg/m2)

24.4 ± 2.8

23.6 ± 2.6

25.9 ± 2.5

<0.001

25.0 ± 3.0*

23.1 ± 2.3

25.9 ± 3.0

<0.001

Current smoking, n (%)

277 (12)

176 (12)

101 (13)

0.500

76 (14)

23 (14)

53 (14)

0.876

SBP (mmHg)

126 ± 15

124 ± 14

130 ± 15

<0.001

128 ± 15†

123 ± 13

130 ± 16

<0.001

DBP (mmHg)

79 ± 10

78 ± 9

81 ± 10

<0.001

78 ± 10

76 ± 9

79 ± 10

<0.001

Antihypertensive treatment, n (%)

1,098 (49)

628 (43)

470 (61)

<0.001

298 (54)†

61 (36)

237 (63)

<0.001

Total cholesterol (mg/dL)

188 ± 35

187 ± 34

190 ± 37

0.047

181 ± 37*

176 ± 36

183 ± 38

0.045

Triglyceride (mg/dL)

140 ± 91

115 ± 61

190 ± 114

<0.001

160 ± 102*

105 ± 50

185 ± 109

<0.001

HDL cholesterol (mg/dL)

51 ± 12

54 ± 12

45 ± 10

<0.001

48 ± 11*

54 ± 11

46 ± 10

<0.001

LDL cholesterol (mg/dL)

120 ± 33

120 ± 32

120 ± 34

0.850

114 ± 38*

115 ± 42

114 ± 36

0.670

Creatinine (mg/dL)

0.90 ± 0.16

0.90 ± 0.16

0.91 ± 0.16

0.182

0.91 ± 0.16

0.91 ± 0.17

0.90 ± 0.16

0.779

GFR (mL/min/1.73 m2)

82 ± 13

82 ± 13

82 ± 13

0.235

83 ± 14

83 ± 14

82 ± 14

0.513

FBS (mg/dL)

95 ± 10

93 ± 9

100 ± 11

<0.001

135 ± 43*

133 ± 42

135 ± 44

0.584

Duration of diabetes (years)

-

-

-

-

11 ± 7

12 ± 7

10 ± 7

0.094

Anti-diabetic treatment, n (%)

-

-

-

-

433 (77)

133 (76)

300 (78)

0.588

Coronary atherosclerosis parameters, n (%)

        

Any plaque

981 (43)

597 (26)

384 (48)

<0.001

359 (64)*

104 (59)

255 (66)

0.108

CMP

797 (35)

480 (32)

317 (40)

<0.001

311 (55)*

96 (55)

215 (56)

0.784

NCP

184 (8)

117 (8)

67 (8)

0.571

48 (9)

8 (5)

40 (10)

0.022

Obstructive plaque

292 (13)

171 (11)

121 (15)

0.007

145 (26)*

44 (25)

101 (26)

0.835

Obstructive CMP

244 (11)

140 (9)

104 (13)

0.005

122 (22)*

39 (22)

83 (22)

0.912

Obstructive NCP

48 (2)

31 (2)

17 (2)

0.876

23 (4)†

5 (3)

18 (5)

0.366

CACS ≥ 100

264 (12)

155 (10)

109 (14)

0.013

129 (23)*

41 (23)

88 (23)

0.946

  1. Data are expressed as n (%) or mean ± SD. CACS, coronary artery calcium score; CAD, coronary artery disease; CMP, calcified or mixed plaque; DBP, diastolic blood pressure; FBS, fasting blood sugar; GFR, glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MetS, metabolic syndrome; NCP, non-calcified plaque; SBP, systolic blood pressure. *P <0.001 vs. no diabetes. †P <0.05 vs. no diabetes.