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Table 4 Risk factors for adverse CV outcomes among non-diabetic CKD patients

From: Clinical significance of subclinical carotid atherosclerosis and its relationship with echocardiographic parameters in non-diabetic chronic kidney disease patients

Parameters Adverse CV events Univariate analysis Multivariate analysis
+ (n = 23) - (n = 159) P HR (95% CI) P
Age (years)† 72.5 ± 11.2 67.2 ± 15.1 0.098 1.05 (0.91-1.01) 0.087
Male, n (%) 13 (56.5) 83 (52.2) 0.740 - -
Smokers, n (%)† 13 (56.5) 57 (35.8) 0.012 3.13 (1.10-9.09) 0.036
Hypertension, n (%)† 20 (87.0) 109 (68.5) 0.043 1.61 (0.88-2.51) 0.101
SBP (mmHg) 138.9 ± 31.0 133.6 ± 19.2 0.181 - -
DBP (mmHg) 78.0 ± 14.0 75.1 ± 11.7 0.150 - -
Pulse pressure (mmHg) 60.9 ± 24.6 58.5 ± 15.8 0.552 - -
BMI (kg/m2) 24.1 ± 3.2 24.3 ± 3.7 0.746   
Serum creatinine (mg/dL) 2.8 ± 3.1 2.7 ± 2.4 0.910 - -
LDL-cholesterol (mg/dL) 100.5 ± 34.1 96.2 ± 41.0 0.684 - -
Urine PCR* -0.97 ± 1.22 -1.2 ± 1.45 0.426 - -
hs-CRP (mg/L) *† 0.03 ± 1.27 -0.23 ± 1.10 0.220 1.22 (0.58-1.28) 0.486
Echocardiography      
 LVH† 13 (56.5) 56(35.2) 0.029 2.01 (0.81-5.34) 0.128
 LVEF 58.3 ± 9.8 59.1 ± 9.7 0.778 - -
 LVMI 112.0 ± 27.9 101.4 ±29.5 0.133 - -
 E/A ratio† 0.64 ± 0.12 0.78 ± 0.30 0.013 0.02 (0.001-0.55) 0.022
 E/E’ ratio† 13.7 ± 5.21 11.3 ± 3.7 0.003 1.10 (1.01-1.21) 0.042
Carotid plaque, n (%)† 18 (78.3) 72(45.3) 0.001 7.80 (1.45-45.97) 0.017
Carotid IMT (mm) † 0.95 ± 0.13 0.84 ± 0.15 0.010 10.58 (0.43-26.87) 0.149
  1. †, p <0.05 between patients with and without adverse CV events. *, log-transformed.