Table 4 Risk factors for adverse CV outcomes among non-diabetic CKD patients
Parameters | Adverse CV events | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
+ (n = 23) | - (n = 159) | P | HR (95% CI) | P | |
Age (years)† | 72.5 ± 11.2 | 67.2 ± 15.1 | 0.098 | 1.05 (0.91-1.01) | 0.087 |
Male, n (%) | 13 (56.5) | 83 (52.2) | 0.740 | - | - |
Smokers, n (%)† | 13 (56.5) | 57 (35.8) | 0.012 | 3.13 (1.10-9.09) | 0.036 |
Hypertension, n (%)† | 20 (87.0) | 109 (68.5) | 0.043 | 1.61 (0.88-2.51) | 0.101 |
SBP (mmHg) | 138.9 ± 31.0 | 133.6 ± 19.2 | 0.181 | - | - |
DBP (mmHg) | 78.0 ± 14.0 | 75.1 ± 11.7 | 0.150 | - | - |
Pulse pressure (mmHg) | 60.9 ± 24.6 | 58.5 ± 15.8 | 0.552 | - | - |
BMI (kg/m2) | 24.1 ± 3.2 | 24.3 ± 3.7 | 0.746 | ||
Serum creatinine (mg/dL) | 2.8 ± 3.1 | 2.7 ± 2.4 | 0.910 | - | - |
LDL-cholesterol (mg/dL) | 100.5 ± 34.1 | 96.2 ± 41.0 | 0.684 | - | - |
Urine PCR* | -0.97 ± 1.22 | -1.2 ± 1.45 | 0.426 | - | - |
hs-CRP (mg/L) *† | 0.03 ± 1.27 | -0.23 ± 1.10 | 0.220 | 1.22 (0.58-1.28) | 0.486 |
Echocardiography | |||||
LVH† | 13 (56.5) | 56(35.2) | 0.029 | 2.01 (0.81-5.34) | 0.128 |
LVEF | 58.3 ± 9.8 | 59.1 ± 9.7 | 0.778 | - | - |
LVMI | 112.0 ± 27.9 | 101.4 ±29.5 | 0.133 | - | - |
E/A ratio† | 0.64 ± 0.12 | 0.78 ± 0.30 | 0.013 | 0.02 (0.001-0.55) | 0.022 |
E/E’ ratio† | 13.7 ± 5.21 | 11.3 ± 3.7 | 0.003 | 1.10 (1.01-1.21) | 0.042 |
Carotid plaque, n (%)† | 18 (78.3) | 72(45.3) | 0.001 | 7.80 (1.45-45.97) | 0.017 |
Carotid IMT (mm) † | 0.95 ± 0.13 | 0.84 ± 0.15 | 0.010 | 10.58 (0.43-26.87) | 0.149 |