Table 2 Clinical scenarios and associated 10-year CVD risk estimates
Clinical scenario (n = number responding to the question in the control group) | Calculated 10-year Framingham risk for coronary artery disease | Mean predicted 10-year cardiovascular risk and interquartile range among respondents in the control group* (N = 243) | p-value for differences between calculated and mean predicted 10-year CVD risk |
|---|---|---|---|
Case 1. A 52 year-old woman with no chronic conditions, no history of tobacco or family history of cardiovascular disease; blood pressure 128/82, pulse 72, BMI 30; after a trial of diet and exercise, total cholesterol 260 mg/dL, triglycerides 145 mg/dL, HDL 56 mg/dL, and LDL-C 175 mg/dL (n = 235) | 2 | 11.2 [9.5-12.8] | <0.001 |
Case 2. A 70 year-old man with hypertension, treated with a thiazide, and osteoarthritis. He quit tobacco 40 years ago; blood pressure 136/80, pulse 70; after a trial of diet and exercise, total cholesterol 208 mg/dL, triglycerides 190 mg/dL, HDL 42 mg/dL, and LDL-C 128 mg/dL (n = 232). | 22 | 19.3 [17.3-21.3] | 0.007 |
Case 3. A 55 year-old woman with hypertension, treated with a calcium channel blocker, and obesity; she smokes 1 pack of cigarettes daily, and has no family history of cardiovascular disease or diabetes; blood pressure 128/82, pulse 72, BMI 32; after a trial of diet and exercise, total choleseterol is 200 mg/dL, triglycerides 125 mg/dL, HDL 40 mg/dL, and LDL-C 135 mg/dL (n = 233). | 7 | 19.7 [17.5-21.9] | <0.001 |
Case 4. A 52 year-old man with hypertension, treated with a thiazide; he smokes 1 pack of cigarettes daily, and has no family history of cardiovascular disease; blood pressure is 128/82, pulse 72; after a trial of diet and exercise, total cholesterol is 145 mg/dL, triglycerides 125 mg/dL, HDL 30 mg/dL, and LDL-C 90 mg/dL (n = 231) | 13 | 16.7 [14.9-18.5] | <0.001 |
Case 5. A 71 year-old man with hypertension, treated with an ace inhibitor, and benign prostatic hyperplasia; he quit tobacco 30 years ago; blood pressure 136/80, pulse 70; total cholesterol 178 mg/dL, triglycerides 190 mg/dL, HDL 44 mg/dL, and LDL-C 96 mg/dL (n = 228) | 21 | 15.9 [14.3-17.5] | <0.001 |