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Table 1 Baseline characteristics of subjects with or without coronary artery disease events over 4 years of follow-up

From: Asymptomatic subjects with diabetes have a comparable risk of coronary artery disease to Non-diabetic subjects presenting chest pain: a 4-year community-based prospective study

 

Subjects without diabetes mellitus

Subjects with diabetes mellitus

No CAD at follow-up

CAD at follow-up

P a

No CAD at follow-up

CAD at follow-up

P a

N (% Men)

7314 (46.5)

57 (40.4)

0.415

1176 (50.9)

27 (48.1)

0.994

  Ansung (% Men)

3289 (43.7)

36 (36.1)

 

595 (43.9)

18 (55.6)

 

  Ansan (% Men)

4025 (48.7)

21 (47.6)

 

581 (58.0)

9 (33.3)

 

Age (years)

51 ± 9

56 ± 9

<0.001

56 ± 9

59 ± 9

0.050

BMI (kg/m2)

24.4 ± 3.1

25.7 ± 2.9

0.001

25.6 ± 3.3

25.5 ± 3.9

0.988

Waist circumference (cm)

Men

83.2 ± 7.5

86.5 ± 6.7

0.032

86.2 ± 8.7

88.5 ± 8.8

0.262

 

Women

80.6 ± 9.5

87.4 ± 7.5

0.001

87.1 ± 8.6

86.6 ± 8.8

0.699

Systolic blood pressure (mmHg)

116 ± 18

121 ± 15

0.249

124 ± 19

126 ± 17

0.986

Diastolic blood pressure (mmHg)

74 ± 12

76 ± 9

0.805

77 ± 11

76 ± 10

0.463

HbA1C (%)

5.5 ± 0.3

5.6 ± 0.4

0.758

7.4 ± 1.6

7.1 ± 1.5

0.513

Fasting glucose (mmol/L)

4.7 ± 0.5

4.7 ± 0.4

0.700

6.9 ± 2.6

6.7 ± 2.5

0.986

Total cholesterol (mmol/L)

4.93 ± 0.90

5.21 ± 0.99

0.031

5.21 ± 1.07

5.01 ± 1.10

0.402

HDL cholesterol (mmol/L)

Men

1.16 ± 0.27

1.25 ± 0.38

0.327

1.11 ± 0.26

1.15 ± 0.29

0.630

 

Women

1.24 ± 0.28

1.22 ± 0.31

0.865

1.14 ± 0.27

1.17 ± 0.23

0.600

Triglyceride (mmol/L)

1.68 ± 1.06

1.95 ± 0.99

0.032

2.31 ± 1.52

2.07 ± 0.96

0.634

Serum creatinine (μmol/L)

74 ± 18

72 ± 14

0.506

76 ± 37

80 ± 28

0.551

Urine microalbuminuria(mg/g Cr)

97 ± 244

79 ± 60

0.665

180 ± 487

182 ± 191

0.623

  Normal (%)

17.2

8.7

 

10.6

0.0

 

  Microalbuminuria (%)

79.3

91.3

0.424

79.4

80.0

0.475

  Proteinuria (%)

3.0

0.0

 

10.0

20.0

 

Smoker

      

  Non-smoker (%)

59.9

57.9

 

56.2

53.3

 

  Ex-smoker (%)

15.1

17.5

0.591

16.8

16.7

0.631

  Smoker (%)

25.0

24.6

 

27.0

30.0

 

Family history of CAD, N (%)

22 (0.3%)

0 (0)

0.998

2 (0.2)

0 (0)

1.000

Hypertension, N (%)

1355 (18.5)

19 (33.3)

0.074

425 (36.1)

14 (51.9)

0.237

Antihypertensive drug, N (%)

591 (8.1)

14 (24.6)

0.001c

260 (22.1)

11 (40.7)

0.090

Hypertension, uncontrolled, N (%)b

990 (13.5)

9 (15.8)

0.393

274 (23.3)

6 (22.2)

0.237

Dyslipidemia, N (%)

3051 (41.7)

34 (59.6)

0.016d

786 (66.7)

18 (66.7)

0.959

Cholesterol-lowering drug, N (%)

20 (0.3)

0

0.998

15 (1.3)

0

0.998

Triglyceride ≥ 1.7 mmol/L, N (%)

2627 (35.9)

31 (54.4)

0.009e

721 (61.5)

17 (63.0)

0.813

LDL cholesterol < 4.1 mmol/L, N (%)

6562 (89.7)

52 (91.2)

0.672

959 (81.8)

22 (81.5)

0.887

LDL cholesterol < 3.3 mmol/L, N (%)

4860 (66.5)

38 (66.7)

0.870

672 (57.3)

18 (66.7)

0.379

LDL cholesterol < 2.6 mmol/L, N (%)

2212 (30.2)

17 (29.8)

0.967

306 (26.1)

11 (40.7)

0.116

HbA1c < 7%, N (%)

-

-

-

609 (51.8)

16 (59.3)

0.423

Living in urban area (Ansan) (%)

51.4%

33.3%

0.150

46.5%

30.0%

0.622

  1. Abbreviations: CAD, coronary artery disease.
  2. aAge-adjusted P value; bCases with systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg irrespective of medication; cOdds ratio (OR) for CAD = 2.829 [1.501- 5.333]; dOR = 1.928 [1.132 – 3.285]; eOR = 2.014 [1.192 – 3.404].
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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