Figure 1

Schematics of fabricating vascular graft with submicron longitudinally aligned topography. (a) Electrospinning PU onto high velocity rotating drum. (b) Removing the aligned nanofibrous mat from the drum. (c) Production of tubular construct by rolling the nanofibrous mat around a metal needle. (d) Electrospinning of random PU nanofibers on the top of aligned tubular scaffold. (e) The vascular graft with aligned intimal topography and random external surface.