Skip to main content

Table 2 Summary of results of previous validation studies of the HEART score

From: The impact of the HEART risk score in the early assessment of patients with acute chest pain: design of a stepped wedge, cluster randomised trial

  Total
Number of patients N = 880 [12] N = 2388 [13] N = 2906 [14] N = 6174
Design Retrospective Prospective Prospective  
Countries The Netherlands The Netherlands 9 countries in the Asia-Pacific region  
Participating hospitals 4 10 14  
Inclusion period Jan ‘06 – Mar ‘06 Oct ‘08 –Nov ‘09 Nov ‘07 – Dec ‘10  
Type of patients Patients presenting with chest pain at the ED Patients presenting with chest pain at the ED Patients presenting with chest pain at the ED  
MACE definition AMI, revascularisation, all cause death AMI, revascularisation, stenosis managed conservatively, all cause death AMI, revascularisation, death unless clearly non-cardiac  
Duration of follow-up 6 weeks 6 weeks 4 weeks  
Cumulative incidence of MACE stratified by HEART scores     
0-3 0.99% 1.7% 1.7% 1.6% (95%-CI 1.05-2.15)
4-6 11.6% 16.6% 14.3% 12.5% (95%-CI 11.34-13.66)
7-10 65.2% 50.1% 50.0% 49.4% (95%-CI 46.37- 52.43)
  1. ED: emergency department.
  2. AMI: acute myocardial infarction.
  3. MACE: major adverse cardiac event.
  4. 95%-CI: 95%- confidence intervals.