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Table 5 HCM screening and the effect of the addition of the troponin measures screening models, using logistic regression with boderline or definite HCM findings at echo as the dependent variable

From: Use of a highly-sensitive cardiac troponin I assay in a screening population for hypertrophic cardiomyopathy: a case-referent study

Model

Covariables

n

Pseudo R2

AUROC (95% CI)

Simple model

Age, sex and symptoms

104

0.177

0.75 (0.65, 0.86)

Screening model

Age, sex, symptoms and “Group 2” ECG changes

104

0.189

0.77 (0.67, 0.87)

Enhanced screening model with cTnI

Age, sex, symptoms, “Group 2” ECG changes and ln(cTnI)

104

0.201

0.75 (0.63, 0.86)

Enhanced screening model with hsTnI

Age, sex, symptoms, “Group 2” ECG changes and ln(hsTnI)

104

0.225

0.78 (0.69, 0.88)

  1. Footnote: Integrated discrimination index (IDI) for the addition of the ln(cTnI) to the “Screening” model is 0.025 (standard error 0.024), p=0.299. Integrated discrimination index (IDI) for the addition of the ln(hsTnI) to the “Screening” model is 0.036 (standard error 0.019), p=0.056.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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