Table 1 Baseline characteristics of the study population, stratified by echocardiographic criteria of HCM 1,3
Total (n = 107) | Normal screening echo (n=64) | Borderline HCM (n=24) | Definite HCM (n=19) | ||
|---|---|---|---|---|---|
Demographic data | |||||
Age in years: mean [SD] | 39.30 (13.86) | 35.63 [12.26] | 44.92 [12.793] | 44.59 [16.63] | F=6.15, p=0.003 |
Male sex: n (%) | 63 (58002E9%) | 32 (50.0%) | 20 (83.3%) | 11 (57.9%) | Χ2=8.01, p=0.018 |
BMI in kg/m 2 : mean [SD] | 26.94 (3.90) | 25.67 (3.90) | 29.08 [3.88] | 27.70 [3.07] | F=5.97, p=0.004 |
Relationship to the family proband | |||||
Proband: n (%) | 8 (7.5%) | 0 (0%) | 1 (4.2%) | 7 (36.85%) | Fishers exact p<0.005 |
1 st degree relative : n (%) | 82 (76.6%) | 53 (82.8%) | 20 (83.3%) | 9 (47.4%) | |
2 nd degree or higher : n (%) | 17 (15.9%) | 11 (17.2%) | 3 (12.5%) | 3 (15.8%) | |
Clinical History | |||||
Any symptoms: n (%) | 36 (33.6%) | 18 (28.1%) | 8 (33.3%) | 10 (52.5%) | Χ2=3.94, p=0.139 |
Chest pain: n (%) | 10 (9.4%) | 7 (10.9%) | 2 (8.3%) | 1 (5.3%) | |
Dyspnoea: n(%) | 12 (11.2%) | 5 (7.8%) | 3 (12.5%) | 4 (21.1%) | Fishers exact p=0.267 |
Palpitations: n(%) | 17 (15.9%) | 7 (10.9%) | 4 (16.7%) | 6 (31.6%) | Fishers exact p=0.089 |
History of syncope: n(%) | 6 (5.6%) | 2 (3.1%) | 2 (8.3%) | 2 (10.5%) | Fishers exact p=0.286 |