Table 1 Study design of the included randomized controlled trials
Study | N(T/C) | Control group | Conventional drugs | Tirofiban | Endpoints§ | Follow up | Quality* | |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Asp | Cpg | Â | Â | Â | Â | Â |
Chen2012 | 27/24 | √ | √ | Nitroglycerin 200 μg within 3 mins then IV 0.15 μg/kg•min for 36-48 h | 10 μg/kg within 3 mins then IV 0.15 μg/kg•min for 36-48 h | (1)(2)(3) | 30d | B |
Fu 2012 | 43/43 | √ | √ | Verapamil 1 mg within 5 mins | 10 μg/kg within 5 mins then IV 0.075 μg/kg•min for 24 h | (1) | - | B |
Guan 2012 | 40/40 | - | - | Verapamil 1 mg within 5 mins | 10 μg/kg within 5 mins then IV 0.075 μg/kg•min for 24 h | (1) | - | B |
He 2012 | 28/28 | √ | √ | Nitroglycerin 200 μg within 3 mins | 10 μg/kg within 3 mins then IV 0.15 μg/kg•min for 24-48 h | (1)(2)(3) | 14d | B |
Luan 2007 | 45/44 | - | - | Nitroglycerin 200 μg within 3 mins | 10 μg/kg within 3 mins | (1)(2)(3) | 7d | B |
Wang2012 | 48/34 | √ | √ | Verapamil 200 μg within 15 mins | 10 μg/kg within 5 mins then IV 0.15 μg/kg•min for 38 h | (1) | - | B |
Wei 2009 | 26/20 | √ | √ | Nitroglycerin 200 μg within 3 mins then IV 0.15 μg/kg•min for 36-48 h | 10 μg/kg within 3 mins then IV 0.15 μg/kg•min for 36-48 h | (1)(2)(3) | 30d | B |
Wu 2012 | 36/36 | √ | √ | Sodium nitroprusside 0.9 μg/kg within 3 mins | 10 μg/kg within 3 mins then IV 0.15 μg/kg•min for 24 h | (1)(2)(3) | 14d | B |
Zhang 2010 | 46/49 | √ | √ | Verapamil 1 mg within 5 mins | 10 μg/kg within 5 mins then IV 0.075 μg/kg•min for 24 h | (1) | - | B |
Zhang 2012 | 21/24 | √ | √ | Verapamil 200 μg within 3 mins | 10 μg/kg within 3 mins then IV 0.15 μg/kg•min for 36-48 h | (1)(2)(3) | 30d | B |