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Table 5 Measures of model accuracy with and without CYP2C19C*2 status information (n=1050)

From: Cytochrome P450 2C19*2 polymorphism in patients with stable coronary heart disease and risk for secondary cardiovascular disease events: results of a long-term follow-up study in routine clinical care

  Basic model* Basic model plus CYP2C19 polymorphism
Model fit   
LR 69.25 (df=15, p<0.0001) 69.80 (df=16, p<0.0001)
AIC 1603.8 1605.2
BIC 1646.1 1650.3
Discrimination   
C-statistic (AUC, 95% CI) 0.693 (0.645-0.742) 0.695 (0.647-0.744)
Calibration   
Integrated discrimination improvement (IDI)   0.00016 (p=0.87)
Net reclassification improvement (NRI)   −1.3% (p=0.60)
  1. * adjusted for age, gender, BMI, school education, , rehabilitation clinic, smoking status, history of diabetes mellitus, PCI, CABG, left ventricular function, HDL-cholesterol, LDL-cholesterol, treatment with lipid-lowering drugs, NT-proBNP [pg/mL].
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