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Table 4 Sensitivity, specificity and predicitve values of high sensitive troponin T analyzed 3 to 4 hours after admission and the combination of troponin and copeptin at admission in the final diagnosis of ACS, NSTEMI and UAP

From: The combination of high sensitivity troponin T and copeptin facilitates early rule-out of ACS: a prospective observational study

 

hsTnT ≤ 14 ng/L and Copeptin < 14 pmol/L at presentation

hsTnT ≤ 14 ng/L after 3-4 hours

p-value

 

(n = 309)

(n = 309)

 

ACS

   

Sensitivity

86 (74-92)

77 (65-86)

0.031

Specificity

50 (44-56)

68 (62-74)

<0.001

NPV

92 (85-96)

91 (86-95)

 

PPV

33 (26-40)

41 (32-50)

 

NSTEMI

   

Sensitivity

98 (87-100)

98 (87-100)

1

Specificity

49 (43-55)

68 (62-73)

<0.001

NPV

99 (95-100)

99 (96-100)

 

PPV

25 (19-32)

35 (27-44)

 

UAP

   

Sensitivity

61 (39-80)

35 (17-57)

0.031

Specificity

42 (37-48)

57 (51-63)

<0.001

NPV

93 (87-97)

92 (86-95)

 

PPV

8 (5-13)

6 (3-12)

 
  1. ACS acute coronary syndrome, NPV negative predicitive value, PPV positive predicitive value, NSTEMI non ST-elevation myocardial infarction, UAP unstable angina pectoris.
  2. Sensitivity, Specificity, NPV and PPV are given with corresponding 95% confidence interval.